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ORIGINAL RESEARCH article

Front. Psychiatry
Sec. Adolescent and Young Adult Psychiatry
Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1520647

Global epidemiologic burden of anxiety syndrome in women of childbearing age between 1990 and 2021, and its association with sociodemographic index

Provisionally accepted
Kaiyuan Li Kaiyuan Li 1Peng Liu Peng Liu 2*Lingyu Han Lingyu Han 3Min Sha Min Sha 3Jun Ye Jun Ye 3Li Zhu Li Zhu 3
  • 1 Dalian University, Dalian, Liaoning Province, China
  • 2 Nanchang University, Nanchang, China
  • 3 Jiangsu Taizhou People's Hospital, Taizhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Background: Anxiety syndrome has emerged as a significant global public health concern, particularly among women of childbearing age (WCBA). However, comprehensive studies examining the global burden and temporal trends of anxiety syndrome in this population remain limited.Methods: Data on the prevalence, incidence, and disability-adjusted life years (DALYs) associated with anxiety syndrome among WCBA from 1990 to 2021 were extracted from the Global Burden of Disease (GBD) database. The estimated annual percentage change (EAPC) was calculated to evaluate temporal trends in disease burden, with 95% uncertainty intervals (UIs) reported for point estimates.Results: In 2021, the global prevalence, incidence, and DALYs of anxiety syndrome among WCBA were 138.3 million, 18.96 million, and 16.45 million cases, respectively-representing increases of 77%, 77%, and 76% since 1990. The burden of anxiety syndrome demonstrated a significant upward trend across all three indicators, with EAPCs of 0.18 (95% CI: 0.02-0.33), 0.21 (95% CI: 0.06-0.36), and 0.17 (95% CI: 0.02-0.32), respectively. Middle sociodemographic index (SDI) countries bore the highest burden, while low-middle SDI countries exhibited the most rapid growth rate.Among the 21 global regions, the majority experienced an increasing trend across all three metrics, with Mexico showing the most pronounced rise, despite a decline in some countries.Over the past 32 years, the global burden of anxiety syndrome among WCBA has risen substantially, particularly in middle-SDI countries and among women aged 45-49. These findings underscore the urgent need for targeted public health interventions in this population to support the Sustainable Development Goals outlined by the World Health Organization.

    Keywords: anxiety syndrome, Women of childbearing age, Global burden of disease, sociodemographic index, DALYs

    Received: 31 Oct 2024; Accepted: 06 Feb 2025.

    Copyright: © 2025 Li, Liu, Han, Sha, Ye and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Peng Liu, Nanchang University, Nanchang, China

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