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ORIGINAL RESEARCH article

Front. Psychiatry
Sec. Aging Psychiatry
Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1461707
This article is part of the Research Topic Healthy Aging in Action: Addressing the Challenges of Cognitive Decline and Dementia and Contributing to a Better Future for Population Aging View all 6 articles

Incidence and influencing factors of Subsyndromal delirium in elderly patients with pancreatic surgery: A prospective study

Provisionally accepted
Huiqing Xu Huiqing Xu 1Yun Wang Yun Wang 1Ningning Xia Ningning Xia 2Kueiching Pan Kueiching Pan 1,2*
  • 1 School of Nursing, Nanjing Medical University, Nanjing, Jiangsu Province, China
  • 2 The BenQ Hospital Affiliated of Nanjing Medical University, Nanjing, Liaoning Province, China

The final, formatted version of the article will be published soon.

    Objective: To prospectively investigatethe incidence and influencing factors of Subsyndromal delirium (SSD) in elderly patients undergoing pancreatic surgery. Methods: According to a prospective observational study, elderly patients (aged ≥60 years) who underwent pancreatic surgery in the pancreatic center of our hospital from August 2023 to February 2024 were selected. Patients were divided into SSD and Normal groups based on the evaluation of the Delirium Rating Scale-revised-98 in the first 1-4 days postoperatively. Multivariate logistic regression was performed to determine the influencing factors, and subject operating characteristic curves were used to assess the predictive effect of risk factors for subsyndromal delirium. Results: A total of 179 elderly pancreatic surgery patients were included in this study. 67 elderly patients developed subsyndromal delirium with an incidence of 37.43%. Multivariable Logistic regression revealed that risk factors for SSD included age, age-adjusted Charlson Comorbidity Index (aCCI), and postoperative fever, while and education level with senior high school or above was found to be protective factors. Receiver operating characteristic (ROC) curve showed that the combination of age and aCCI predicted SSD in elderly pancreatic surgery patients (Area Under Curve = 0.815, 95% Confidence Interval: 0.752 - 0.878), with sensitivity and specificity of 80.6% and 75.9%, respectively. Conclusion: The incidence of subsyndromal delirium after elderly pancreatic surgery was as high as 37.43%. Effective assessment and prevention of subsyndromal delirium are crucial. In the early postoperative period, special attention should be given to elderly patients with more preoperative comorbidities and lower education levels, and their temperature should be monitored in a timely manner.

    Keywords: subsyndromal delirium, postoperative, Risk factors, Pancreas, Elderly

    Received: 09 Jul 2024; Accepted: 03 Jan 2025.

    Copyright: © 2025 Xu, Wang, Xia and Pan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Kueiching Pan, School of Nursing, Nanjing Medical University, Nanjing, 211166, Jiangsu Province, China

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