AUTHOR=Qu Wei , Wang Xuyi , Dong Chongyang , Zhang Tao , Yin Shugui , Sun Zhijun , Wang Shiqiang , Guo Anni , Hao Wei TITLE=Evaluating the antagonist effect of naltrexone implant via opioid challenge tests with escalating doses of hydromorphone injection in former heroin dependent patients JOURNAL=Frontiers in Psychiatry VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1441598 DOI=10.3389/fpsyt.2025.1441598 ISSN=1664-0640