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SYSTEMATIC REVIEW article

Front. Psychiatry
Sec. Anxiety and Stress Disorders
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1495418

Acupuncture and related therapies for anxiety and depression in patients with premature ovarian insufficiency and diminished ovarian reserve: a systematic review and meta-analysis

Provisionally accepted
Sidan Huang Sidan Huang Danni Zhang Danni Zhang Xuliang Shi Xuliang Shi *Yi Zhang Yi Zhang Xuesong Wang Xuesong Wang Yanfen She Yanfen She Ce Liang Ce Liang Xinyue Li Xinyue Li
  • Hebei University of Chinese Medicine, Shijiazhuang, China

The final, formatted version of the article will be published soon.

    The decreased ovarian function has a negative impact on the mental health of women and increases the risk of anxiety and depression. A growing number of clinical studies have demonstrated that acupuncture-related therapies can effectively and safely restore hormone levels and improve ovarian reserve function. However, the effectiveness of acupuncture-related therapies in alleviating anxiety and depression symptoms in patients with ovarian hypofunction has not been thoroughly evaluated. Therefore, this study conducted a systematic review and meta-analysis to assess the impact of the different acupuncture-related therapies on the mental health of patients with ovarian hypofunction.We comprehensively searched eight famous databases for randomized controlled trials before October 30, 2024. Databases include PubMed, Web of Science, EMBASE and Cochrane Library, China Biomedical (CBM), China National Knowledge Infrastructure (CNKI), Wanfang Database and VIP Database.The study included 12 RCTs, involving 780 patients with ovarian hypofunction, including 403 patients with POI, 297 patients with DOR, and 80 patients with POF. Acupuncture-related therapy was obviously superior to hormone therapy in relieving anxiety symptoms (SMD: -0.90; 95%CI: -1.28, -0.53; P<0.000 01) and depressive symptoms (SMD: -0.82; 95% CI: -1.25, -0.40; P=0.0001). Conclusions: Acupuncture-related therapy was more effective than hormone therapy in improving anxiety and depression symptoms in patients with ovarian hypofunction. This study supports the use of acupuncture-related therapies for women experiencing decreased ovarian function associated with mental health issues.

    Keywords: Acupuncture, PREMATURE OVARIAN INSUFFICIENCY, diminished ovarian reserve, Anxiety, Depression, Meta-analysis

    Received: 12 Sep 2024; Accepted: 06 Nov 2024.

    Copyright: © 2024 Huang, Zhang, Shi, Zhang, Wang, She, Liang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xuliang Shi, Hebei University of Chinese Medicine, Shijiazhuang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.