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SYSTEMATIC REVIEW article

Front. Psychiatry
Sec. Digital Mental Health
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1493823

A Meta-analysis of the relationship between anxiety and non-suicidal self-injury based on Knowledge graphs

Provisionally accepted
Jieyao Shi Jieyao Shi 1Pan Gao Pan Gao 1Bingqian Zhou Bingqian Zhou 2Zhisheng Huang Zhisheng Huang 3,4*
  • 1 Suzhou Vocational Health College, Suzhou, Jiangsu Province, China
  • 2 Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
  • 3 VU Amsterdam, Amsterdam, Netherlands
  • 4 Mental Health Center of Tongji University, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China

The final, formatted version of the article will be published soon.

    Objective The existing research on the relationship between anxiety and non-suicidal self-injury (NSSI) is inconsistent, and there is no systematic review on this area. This study aims to explore the relationship between anxiety and NSSI, in order to provide evidence-based medicine evidence for the early identification of preventable occurrence factors of NSSI.The semantic query (i.e. SPARQL) method was used to retrieve the anxiety-related literature on the Knowledge graph of NSSI, which consist of the metadata and semantic annotation data of English literature related to non-suicidal self-injury in PubMed by June 2023. Two researchers strictly followed the inclusion and exclusion criteria for independent literature screening. After evaluating the quality of the included studies, the selected data was subjected to meta-analysis using RevMan5.3 software.A total of 14 studies met the inclusion criteria of the meta-analysis, including 44064 subjects. The results showed that the proportion of anxiety in the NSSI group was significantly higher than that in the non-NSSI group, and the difference between the groups was statistically significant (OR=3.60, 95% Cl=2.08-6.22, p<0.01).There is a significant correlation between anxiety and NSSI, which is a possible risk factor for NSSI. However, due to limitations of the design type, quantity, and quality of the included study, further research is needed on the causal relationship between anxiety and NSSI. Furthermore, we show that using knowledge graphs is an effective approach to retrieve literature for meta-analysis.

    Keywords: Non-suicidal self-injury1, anxiety2, meta-analysis3, Knowledge graph4, SPARQL5

    Received: 09 Sep 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Shi, Gao, Zhou and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhisheng Huang, VU Amsterdam, Amsterdam, Netherlands

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.