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MINI REVIEW article

Front. Psychiatry
Sec. Mood Disorders
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1492415
This article is part of the Research Topic Non-Neuronal Cells in Neurodegenerative Diseases and Psychiatric Disorders View all 5 articles

Stem cell therapy for the treatment of psychiatric disorders: A real hope for the next decades

Provisionally accepted
Rosa Villanueva Rosa Villanueva 1,2,3,4*
  • 1 University Hospital La Paz, La Paz, Madrid, Spain
  • 2 Departament of psychatry and menta Heath H.Universitario la Paz,, Madrid, Asturias, Spain
  • 3 University Hospital La Paz Research Institute (IdiPAZ), Madrid, Madrid, Spain
  • 4 Autonomous University of Madrid, Madrid, Madrid, Spain

The final, formatted version of the article will be published soon.

    In this review, it is evaluated the progress in the application of stem cell therapy to ameliorate the symptoms of bipolar disorder, major depression, schizophrenia, and autism. These disorders are highly prevalent in clinical medicine and are responsible for high levels of psychosocial disability among patients. All of them share common biomedical features, such as complex and variable genetic substrates, significant susceptibility to environmental changes, and insufficient knowledge of their pathogenesis. In addition, the responsiveness of patients to pharmacological treatment is heterogeneous, and in some cases, no treatment is available. Therefore, the development of stem cellbased regenerative medicine and its possible combination with emerging therapeutic approaches that promote neural plasticity are expected to advance neuropsychiatry in the next few decades.

    Keywords: Bipolar Disorder, Schizophrenia, major depression, treatment-resistant depression, Autism Spectrum Disorder

    Received: 06 Sep 2024; Accepted: 16 Dec 2024.

    Copyright: © 2024 Villanueva. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Rosa Villanueva, University Hospital La Paz, La Paz, 28046, Madrid, Spain

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.