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ORIGINAL RESEARCH article

Front. Psychiatry
Sec. Psychopharmacology
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1471083
This article is part of the Research Topic Substance Use Disorder: Above and Beyond Addiction, Volume II View all 14 articles

Passiflora incarnata L., herba, in Benzodiazepine Tapering: long-term safety and efficacy in a real-world setting

Provisionally accepted
Matteo Carminati Matteo Carminati 1*Mattia Tondello Mattia Tondello 1Raffaella Zanardi Raffaella Zanardi 1,2
  • 1 Vita-Salute San Raffaele University, Milan, Lombardy, Italy
  • 2 San Raffaele Hospital (IRCCS), Milan, Lombardy, Italy

The final, formatted version of the article will be published soon.

    Aim of the present study was to confirm the possible role of P. incarnata L., herba as an add-on treatment for BDZ tapering, and its efficacy in maintaining BDZ discontinuation over time. We confirmed this effect to be sustained over time, and P. incarnata showed to be easily discontinued with no rebound, withdrawal or psychological dependence effect. Moreover, we investigated possible risk factors for a poor outcome of BDZ tapering, highlighting a possible role of personality disorders as the most relevant clinical factors associated with a not complete BDZ discontinuation.

    Keywords: Matteo Carminati: Conceptualization, Data curation, Formal analysis, investigation, Writing -original draft. Mattia Tondello: Data curation, Writing -original draft. Raffaella Zanardi: Conceptualization, supervision, Writing -original draft

    Received: 26 Jul 2024; Accepted: 13 Sep 2024.

    Copyright: © 2024 Carminati, Tondello and Zanardi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Matteo Carminati, Vita-Salute San Raffaele University, Milan, 20132, Lombardy, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.