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ORIGINAL RESEARCH article

Front. Psychiatry
Sec. Psychological Therapy and Psychosomatics
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1450860

Psychological Distress in Biliary Tract Malignancy Patients: Influencing Factors and Development of a Predictive Nomogram Model

Provisionally accepted
zhennan gou zhennan gou *yuhua liu yuhua liu *wenjie tang wenjie tang *Changming Zhou Changming Zhou zhenqi lu zhenqi lu *lu wang lu wang *Wei Feng Wei Feng *weiqi xu weiqi xu *Jun Wang Jun Wang *
  • Shanghai Cancer Center, Fudan University, Shanghai, China

The final, formatted version of the article will be published soon.

    Objective: This study aims to investigate the psychological distress and its influencing factors in patients with biliary tract malignant tumors, alongside the development of a predictive model.: A total of 219 patients diagnosed with biliary tract malignant tumors who were admitted to the Department of Liver Surgery at Fudan University Shanghai Cancer Center from July 2021 to May 2023, were selected using a convenience sampling method. Research tools involve psychological distress management screening tools, a demographic questionnaire, self-rating anxiety and depression scales, and the Chinese version of the Memorial Symptom Assessment Scale. Bootstrap method was utilized for repeated sampling to identify relevant factors influencing psychological distress in biliary tract cancer patients. The R software was employed to create a nomogram model, and the model's accuracy and predictive performance were assessed using the receiver operating characteristic curve (ROC) and the Hosmer-Lemeshow test. Results: The average score of psychological distress among the 219 patients was (3.91±2.44), with a psychological distress detection rate of 54.8%. Regression model results indicated that factors such as the presence of distant metastasis, comorbidity with other major diseases, poor sleep quality, anxiety, and severity of anxiety and depression were the primary influencers of psychological distress. Conclusion: The detection rate of psychological distress in patients with biliary tract malignant tumors is notably high. The predictive model constructed in this study exhibits good predictive efficacy and clinical value, providing valuable reference for healthcare professionals in developing targeted intervention strategies.

    Keywords: Biliary tract cancer, Psycho-oncology, psychological distress, nomogram, Prediction model, model validation

    Received: 18 Jun 2024; Accepted: 15 Nov 2024.

    Copyright: © 2024 gou, liu, tang, Zhou, lu, wang, Feng, xu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    zhennan gou, Shanghai Cancer Center, Fudan University, Shanghai, China
    yuhua liu, Shanghai Cancer Center, Fudan University, Shanghai, China
    wenjie tang, Shanghai Cancer Center, Fudan University, Shanghai, China
    zhenqi lu, Shanghai Cancer Center, Fudan University, Shanghai, China
    lu wang, Shanghai Cancer Center, Fudan University, Shanghai, China
    Wei Feng, Shanghai Cancer Center, Fudan University, Shanghai, China
    weiqi xu, Shanghai Cancer Center, Fudan University, Shanghai, China
    Jun Wang, Shanghai Cancer Center, Fudan University, Shanghai, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.