AUTHOR=Dell’Osso Liliana , Nardi Benedetta , Bonelli Chiara , Gravina Davide , Benedetti Francesca , Amatori Giulia , Battaglini Simone , Massimetti Gabriele , Luciano Mario , Berardelli Isabella , Brondino Natascia , De Gregorio Marianna , Deste Giacomo , Nola Marta , Reitano Antonino , Muscatello Maria Rosaria Anna , Pompili Maurizio , Politi Pierluigi , Vita Antonio , Carmassi Claudia , Cremone Ivan Mirko , Carpita Barbara , Maj Mario TITLE=Investigating suicidality across the autistic-catatonic continuum in a clinical sample of subjects with major depressive disorder and borderline personality disorder JOURNAL=Frontiers in Psychiatry VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1124241 DOI=10.3389/fpsyt.2023.1124241 ISSN=1664-0640 ABSTRACT=Background

Recent literature has highlighted that catatonia may be more prevalent among psychiatric patients than previously thought, beginning from autism spectrum disorders (ASD), for which it has been suggested to represent a severe late consequence, but also among individuals with mood disorders and borderline personality disorder (BPD). Interestingly, one critical point shared by these conditions is the increased risk of suicidality. The aim of this study was to evaluate how the presence and the prevalence of catatonic symptoms may shape and correlate with suicidal risk in a sample of individuals with major depressive disorder (MDD) or BPD.

Methods

We recruited two clinical samples of subjects (BPD and MDD) and a control group without a diagnosis according to DSM-5 (CTL). Subjects were assessed with the catatonia spectrum (CS) and the MOODS-SR for evaluating suicidality.

Results

In the total sample, suicidality score was significantly and positively correlated with all CS domains and CS total score. Correlation and regression analyses highlighted specific patterns of association among Catatonia spectrum domains and suicidality in the MDD and BPD group and in the total sample.

Conclusion

In both disorders, higher catatonic traits are linked to higher suicidal tendencies, confirming the high risk of suicide for this population. However, different patterns of association between catatonic symptoms and suicidality were highlighted in the two disorders.