- 1Mental Illness Research, Education and Clinical Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States
- 2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States
- 3Center for Health Equity Research and Promotion, Corporal Michael J. Crescenz VA Medical Center, Philadelphia PA, United States
- 4James J. Peters VA Medical Center, Bronx, NY, United States
- 5Department of Family Medicine, University of Colorado Anschutz School of Medicine, Aurora, CO, United States
- 6Behavioral Health Quality Enhancement Research Initiative, Central Arkansas Veterans Healthcare System, Little Rock, AR, United States
- 7Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, United States
- 8VA Rocky Mountain Mental Illness Research, Education and Clinical Center for Suicide Prevention, Rocky Mountain Regional VA Medical Center, Aurora, CO, United States
- 9Division of Hospital Medicine, University of Colorado Anschutz School of Medicine, Aurora, CO, United States
Introduction: Lethal means safety counseling (LMSC) is an evidence-based suicide prevention intervention during which providers encourage patients to limit their access to lethal means (e.g., firearms, medications). Despite agreement about the importance of LMSC, it is underutilized in clinical practice.
Methods: To better understand the individual and contextual factors that influence LMSC and its implementation, we conducted a systematic review of qualitative studies examining stakeholder perceptions of the intervention. PubMed and PsycInfo were searched up to February 2021 using terms related to: (1) LMSC, firearms, or medications; (2) suicide, safety, or injury; and (3) qualitative methodology. Two coders used thematic synthesis to analyze findings from eligible papers, including developing a codebook and coding using an inductive and iterative approach (reliability k > 0.70). Confidence in review findings were evaluated using the Confidence in the Evidence from Reviews of Qualitative Research (CERQual) Approach. Subthemes were assigned to domains in the Consolidated Framework for Implementation Research.
Findings: Of the 19 papers identified, 18 discussed LMSC for firearms and 1 focused exclusively on LMSC for medications. The firearm-related studies explored perspectives of a variety of stakeholders (patients, providers, members of the firearms community, healthcare leaders, and family members) across multiple settings (emergency departments, pediatric and adult primary care, and outpatient mental health). Seven overarching themes emerged, including the: (1) importance of firearms to owners’ identities and perceptions of ownership as a value and right, which can lead to perceived cultural tensions in clinical settings; (2) importance of patients understanding the context and rationale for LMSC; (3) value of providers showing cultural competency when discussing firearms; (4) influence of safety and risk beliefs on firearm behaviors; (5) need to navigate logistical concerns when implementing LMSC; (6) value of individualizing LMSC; (7) potential for trusted family members and friends to be involved in implementing LMSC.
Conclusion: This synthesis of the qualitative literature informs clinical, operational, and research endeavors aimed at increasing the reach and effectiveness of LMSC. Future research should address the perspectives of individuals underrepresented in the literature (e.g., those from racial/ethnic minority groups) and further examine stakeholders’ perceptions of LMSC for medication. [-2pt]
Systematic review registration: [https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021237515], identifier [CRD42021237515].
Introduction
Suicide is the 10th leading cause of death in the United States (US), and suicide rates have increased by about 30% since 1999 (1). The majority of suicide deaths are by firearm injury (51%) and poisoning (14%), often by medication overdose. Lethal means safety counseling (LMSC) is a clinical intervention during which healthcare providers encourage patients to voluntarily remove lethal means (e.g., firearms) from their households or store them more safely to reduce their suicide risk (2, 3). LMSC can be delivered by a variety of providers across a range of clinical settings [e.g., emergency departments, mental health, primary care; (4, 5)], but has typically been directed towards individuals at increased risk for suicide or unintentional injury. Despite broad clinical agreement about the importance of LMSC, there is substantial variability in implementation of this evidence-based intervention across clinical settings, even among high-risk patient populations (6, 7).
Reasons for variation in delivery of LMSC are not fully understood. A systematic review of quantitative studies showed that both providers and patients, particularly those who own firearms, are hesitant to engage in LMSC, that provider training and greater perceived efficacy in counseling increase the delivery of LMSC, and that providers report offering counseling more consistently for those believed to be at higher risk of suicide or firearm injury (6). Qualitative studies are critical for explaining the individual and contextual factors that influence intervention implementation (8–10), especially for interventions about sensitive topics (e.g., firearm safety) that must address the views and concerns of a variety of stakeholders to be successful (11, 12). While qualitative studies are limited by their exploratory nature and small sample sizes, a synthesis of qualitative studies allows for the identification of themes that are consistent across multiple individual studies.
We therefore aimed to conduct a systematic review of qualitative studies to examine: (1) stakeholders’ perceptions of LMSC, especially the barriers and facilitators to its implementation, as well as the role of intervention characteristics and contextual factors on perceptions of acceptability and feasibility; (2) differences in perceptions of LMSC based on stakeholder group and clinical setting; and (3) the implications of stakeholder perceptions for informing LMSC implementation and future research directions. To help conceptualize our findings and describe ways in which stakeholder perceptions may impact the delivery and implementation of LMSC, we categorized subthemes based on domains in the Consolidated Framework for Implementation Research (CFIR), a widely used implementation framework (13).
Methods
The protocol for this review was published on PROSPERO in March 2021, following database searching and prior to screening records for inclusion (PROSPERO ID CRD42021237515). We followed ENTREQ [Enhancing transparency in reporting the synthesis of qualitative research; (14)] and, where applicable, PRISMA reporting guidelines [Supplementary Tables 1, 2; (15)]. As we did not collect primary data, we did not seek IRB approval or patient consent.
Search strategy
We conducted a comprehensive search for studies by searching PubMed and PsycInfo from inception to February 2021 for terms relevant to (1) lethal means in general and firearms and medications in particular, including medications most frequently used for overdose (16); (2) suicide, safety, and injury; and (3) qualitative data (see Object S1 for full search terms). Terms for qualitative data were based on guidance from previous qualitative review papers (17, 18), compilations of relevant Medical Subject Heading (MeSH) terms, and discussions with an information scientist. Following guidance for the conduct of qualitative reviews (10), we supplemented database searches by reviewing eligible papers for relevant citations and contacting corresponding authors of eligible papers to request additional published or in-press papers on similar topics. After removing duplicates, we screened 7,593 abstracts obtained from database searching and 14 from other sources using Covidence software (Figure 1). In total, 207 full texts were reviewed. At each stage, two authors (SS, EM, or KM) reviewed each record and disagreements were resolved by a separate author (GK, during abstract screening) or consensus discussions (during full text screening).
Inclusion and exclusion criteria
Included studies examined stakeholders’ perspectives on LMSC, defined as healthcare providers discussing with patients their access to or storage of lethal means, even if other topics were addressed. We included all types of healthcare providers and defined stakeholders as anyone impacted by LMSC, including healthcare providers and leaders, patients, patients’ family members, or members of impacted communities (e.g., firearm owners). We included studies regardless of whether the intent of LMSC was to prevent suicide, homicide, unintentional injury, or a combination of these outcomes, as the components of counseling have significant overlap across outcomes and findings from these studies are therefore informative (19). Most studies focused on LMSC for suicide risk, although several studies in pediatric settings included LMSC for unintentional injury or homicide (20–22). No exclusions were made based on participants’ demographic or clinical characteristics. As LMSC typically includes discussions about firearms and/or medications that can be used for overdose (2), we included terms relevant to these means in our searches. We also included terms describing LMSC more generally (e.g., “means safety,” “means restriction”) and did not exclude studies based on the types of lethal means addressed.
Studies needed to include qualitative assessment (e.g., interviews, focus groups) and analysis (e.g., descriptive analyses, interpretive analyses) methods (9, 23, 24). We therefore included mixed-methods studies, but excluded those in which the qualitative component consisted only of open-ended survey questions or similar data sources. According to guidelines for qualitative syntheses (25, 26), we included only peer-reviewed studies. We excluded two studies that briefly summarized preliminary qualitative data collected for another study (27, 28). Papers that were from the same parent study were marked as such (Table 1). We analyzed these as separate studies because each presented unique data and no participants overlapped. As concerns related to firearms and medications might differ, particularly due to the cultural significance of firearms in the US (29), we synthesized findings about firearms and medications separately.
Study quality assessments
We assessed study quality using the Critical Appraisal Skills Program (30), which includes three sections evaluating the validity of results, clarity and rigor of findings, and value of the research. We also assessed comprehensiveness of reporting using the Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist (31), which includes three sections evaluating reporting of research reflexivity, study design, and analysis and findings (summaries in Table 2 and details in Supplementary Tables 3–7). Two authors evaluated each study using CASP (SK and GK) and COREQ (KH and GK), and resolved disagreements through consensus discussions.
We followed recent guidelines by not basing inclusion decisions on quality ratings and instead assessing our level of confidence in the main review findings using the CERQual (Confidence in the Evidence from Reviews of Qualitative Research) Approach (8, 32). CERQual is recommended by the Cochrane Qualitative and Implementation Methods Group and involves evaluating findings according to their methodological limitations, coherence, adequacy of data, and relevance, and assigning confidence ratings based on these criteria (Table 3 and Supplementary Table 8). One author assigned confidence ratings for overarching analytic themes (GK) and another author (BH) reviewed and verified these findings; conflicts were resolved via consensus.
Data extraction and analysis
Prior to analyses, the author team discussed their experiences, beliefs, and biases related to lethal means and LMSC to enhance their awareness of these factors and help manage biases during data interpretation and presentation (33). We then synthesized and interpreted findings from primary studies using thematic synthesis, an adaptation of thematic analysis for research synthesis that allows for the development of analytic themes in primary studies (9, 24, 34). Consistent with prior work (34–36), we considered the full results and discussion sections of each paper as data and imported these into NVivo. Two authors (GK and SK) reviewed all papers in detail, identified and discussed recurring concepts, developed a codebook, and coded data line-by-line using an inductive and iterative approach (9, 37). Five papers (26%) were double-coded to ensure consistency. We used coding comparisons to produce inter-rater reliability metrics that were used to understand coding discrepancies and refine the codebook. A third author (JS) also reviewed the materials and provided input on the codebook. The average kappa was 0.89 with a range of 0.71 to 1.0.
The two authors first categorized data using broad, descriptive codes such as barriers identified by patients and stakeholder recommendations for increasing LMSC acceptability. These codes were then subcategorized into detailed subthemes. Three authors (GK, KH, and JS) reviewed and consolidated these subthemes, and then organized them into overarching analytic themes. Additionally, these authors assigned subthemes to relevant CFIR domains (e.g., Intervention Characteristics) to help conceptualize ways in which stakeholder perceptions of LMSC may impact its implementation (13, 38).
After coding the qualitative data, we applied second-level codes for stakeholder group and clinical setting, as previous research suggests that there are important distinctions among these factors (6, 12, 39). For example, if a paper only reported provider perceptions it was coded as such, but if a paper reported provider and patient perceptions, passages in the paper were coded as perceptions of providers or patients, respectively. Stakeholder group codes included providers and patients, as well as firearm owners and non-owners. Clinical setting codes included emergency departments, pediatric primary care, and adult primary care. We did not code for settings with fewer than three relevant studies due to concerns about making comparisons with insufficient information (Table 1).
Results
Characteristics of studies
Nineteen eligible papers were identified (Figure 1), of which 16 addressed LMSC exclusively for firearms, 1 addressed LMSC exclusively for medications (40), and 2 addressed LMSC for both firearms and medications [(41, 42); Table 1]. Given the paucity of medication-related data, we briefly summarized findings on medication-related LMSC and focused our main analyses on firearm-specific LMSC.
Studies examined LMSC in the following settings (Table 1): emergency departments (41–44), pediatric primary care (21, 22, 45, 46), adult primary care (47–49), outpatient mental health (50, 51), and outside of any specific clinical setting (20, 52–55). Stakeholder groups included healthcare providers (22, 41, 43–45, 50, 51, 53), patients (20–22, 42, 45, 48, 49, 51, 54, 55), firearm owners or those with firearm expertise (20, 46, 51, 52, 54, 55), healthcare leaders (45, 51), community members (22, 47), and family members (43, 51), with many studies including more than one group or overlapping groups. Finally, five studies focused on veteran participants (47, 48, 51, 54, 55).
Thematic synthesis
Table 3 includes summaries of overarching analytic themes and subthemes, as well as supporting quotes and the studies contributing to each theme. Figure 2 presents the subthemes grouped according to the CFIR domain to which they were assigned. The first CFIR domain, Intervention Characteristics, refers to aspects of an intervention that impact its implementation success; we assigned subthemes describing stakeholder suggestions for improving LMSC acceptability to this domain. We included subthemes relevant to the overall framing of the intervention, each intervention component, patient preferences for providers to deliver LMSC, and ways to adapt the intervention. Characteristics of Individuals (domain 2) refers to individuals’ beliefs, knowledge, personal characteristics, and values that impact implementation; subthemes describing stakeholder perceptions of barriers and facilitators to LMSC implementation were assigned to this domain. Inner Setting (domain 3), refers to characteristics of the implementation setting; subthemes describing the relevance of clinical contexts to LMSC implementation were assigned to this domain. Outer Setting (domain 4) refers to external influences on intervention implementation; subthemes describing sociopolitical beliefs about firearms were assigned to this domain. Finally, Process of Implementation (domain 5) refers to stages of implementation (e.g., planning and executing); one subtheme related to partnering with stakeholders during LMSC implementation was assigned to this domain. Subthemes within Inner Setting, Outer Setting, and Process of Implementation were not labeled as barriers or facilitators because they can be conceptualized as either depending on how they are viewed and addressed by stakeholders (56).
Theme 1: Perceptions of firearms as a value and right leads to a cultural divide
Firearm owners perceived firearms as being important to their identities and believed that firearms have value and that owning them is a protected and private right. These views led to perceived cultural tensions between patients and providers and hesitancy to discuss firearms. Three relevant sociopolitical beliefs about firearms were identified. First, firearms have sentimental and practical value, including for hunting, socializing, employment purposes (e.g., military service), and personal protection (20, 21, 45, 48–50, 52, 54, 55). Second, firearms ownership was viewed as justified by Constitutional rights, rights to protect oneself and one’s family, and rights to privacy, which could be jeopardized by disclosing firearm ownership to providers or limiting access to them (21, 44–52, 54). Third, patients and providers perceived a cultural divide regarding firearms, which was seen as a divide between patients who own firearms and providers who were typically assumed to be non-owners. This divide led providers and patients to hesitate to engage in LMSC (20, 21, 42, 44–46, 48–50, 52). On the other hand, providers familiar with firearms noted that referencing these experiences gave them credibility when conducing LMSC (21, 50).
The perceived cultural divide about firearms related to patient and provider barriers to engaging in LMSC. Some patients thought that providers should not be involved in firearm-related discussions and that ownership disclosure may lead to losing firearm access or government tracking (21, 44–52, 54). Patients also felt judged by providers when disclosing firearm ownership based on their perceptions of providers’ verbal responses and body language, as well as assumptions that providers were only asking certain patients about firearm safety (20, 21, 45–47, 54). Finally, providers described how cultural and political tensions surrounding firearms made it challenging to discuss patients’ safety while not offending patients or negatively impacting their relationship with them (21, 44, 45, 51).
Theme 2: Acceptability of lethal means safety counseling depends on its rationale and context
Patients and providers noted that the acceptability of LMSC depends on its context and rationale. They generally agreed that LMSC was acceptable and feasible for patients at elevated risk for suicide or in mental distress, and for parents of children and adolescents. Although some patients and providers thought that LMSC would be acceptable and feasible as a universal intervention for adults, others did not (21, 22, 41, 44–48, 51, 55). Patients’ comprehension of the rationale for LMSC, including protecting those vulnerable to suicides or injuries, can facilitate their engagement in it (20, 41, 43, 48, 49). Relatedly, patients prefer discussing firearms with someone they trust and with whom they have a preexisting relationship, which may be their doctor or other members of their treatment team (22, 43, 45, 47, 50, 51, 54, 55). Additionally, stakeholders noted that LMSC would be more acceptable if it included a rationale for discussing firearms, was incorporated into conversations about home safety, other health behaviors (e.g., car seats), or other lethal means (e.g., medications), and accounted for the role of other factors when appropriate (e.g., previous traumatic events) (20, 21, 41, 45–50, 52, 54, 55).
A point of disagreement was whether and in which contexts providers should ask patients if they have access to firearms (21, 43, 44, 46, 47, 49, 51). Some patients and providers preferred that providers offer advice about storing firearms without explicitly asking about firearm ownership to sidestep patients’ concerns about firearm rights and privacy, and because firearm ownership is already so common in some communities (21, 46, 47). Others noted that information about firearm access helps providers offer more targeted storage solutions and said that if these questions were asked more regularly, patients would be more willing to answer them (43, 44, 49). Firearm stakeholders in particular recommended that information about ownership not be placed in patients’ medical records (46).
Theme 3: Providing training to increase cultural competency
Both patients and providers highlighted the role of cultural competency in facilitating discussions about firearms, and noted that training providers to understand more about firearms, firearm culture, and suicide risk related to firearms may improve their competency and confidence in delivering LMSC. Providers perceived their lack of experience with firearms as a barrier to discussing firearm storage with patients (21, 43, 45, 51, 53). Relevant training, however, as well as supporting materials like free locking devices to give to patients, decision tools for firearm storage (e.g., Lock to Live), and written materials for patients could facilitate providers’ implementation of LMSC (21, 41, 43–47, 50, 51, 53). Additionally, firearm stakeholders recommended that health systems partner with firearm advocacy groups to provide resources that firearm owners may perceive as more credible or acceptable (45, 46).
Providers and patients also noted ways in which cultural competency can shape the delivery of LMSC. First, they recommended that providers acknowledge the value and role of firearms in people’s lives and identities, as well as appeal to the pre-existing culture of safety within the firearm community (20, 21, 50, 52, 55). Second, they noted that providers should remain non-judgmental, respectful, and aware of their own biases when discussing firearms. Specifically, providers were asked to convey their concern for the patient and try to establish a genuine connection to them, while at the same time remaining professional and impersonal about the details of firearm access and storage (21, 45, 47, 48, 50). Third, suggestions related to the recommendation of storage options included tailoring recommendations to patients’ reasons for owning firearms, offering a range of storage options to fit patients’ individual needs, emphasizing the temporary nature of limiting access to firearms during high-risk periods to encourage behavior change, and providing specific storage options to help focus individuals in emotional distress (21, 41–43, 51, 52, 55). Fourth, stakeholders made note of additional components of LMSC that may facilitate its implementation. These included providing written information to patients about firearm storage or suicide risk, describing examples of patients who stored their firearms more securely following LMSC, or referring patients to other organizations to provide them with additional services or firearm safety training (20, 22, 41, 45, 46, 51–53). Finally, patients expressed a preference for discussing firearms with a provider who owns firearms or understands values related to firearms, as they perceived these individuals to have more credibility and understanding of their situation (20, 46, 48, 52).
Theme 4: Beliefs about safety and risks of secured and unsecured firearms
Firearm owners generally perceived firearms and unsecured firearms as contributing little to suicide risk, and overall prioritized safety in terms of personal and household protection. In fact, securing firearms increased the chance of not having access to them when needed for personal or household protection. Firearm owners stated that their valuation of safety motivated them both to have easy access to firearms for protection and to practice responsible ownership (20, 42, 45, 46, 51, 52, 55). Responsible ownership included preventing unauthorized access to firearms and practicing safe handling (46, 52, 55), as well as introducing firearms to children and teaching them to respect firearms and handle them safely (20, 46). These practices were for the purposes of preventing unintentional injury rather than suicide.
Beliefs about safety and risk were related to several patient barriers to LMSC. First, patients perceived the risk of unsecured firearms in terms of suicide or unintentional injury as low compared to other safety risks (e.g., access to alcohol, risk of victimization) for themselves and their families, and prioritized easy access to their firearms for self-defense (20–22, 50, 51, 55). Second, some patients expressed the belief that storing firearms safely would not prevent suicides or unintentional injuries as such incidents are inevitable (20, 49). Third, patients noted that conventional locks, particularly trigger and cable locks, were inconvenient to use and might hamper self-defense efforts. Some reported that these locks were often unused or disposed of when they were provided (20, 42, 46, 52). Although biometric storage devices were perceived as less problematic, their cost was a deterrent (20). These views led patients and providers to recommend that locking devices be provided or subsidized by the healthcare system, but there were conflicting opinions about the feasibility of funding and distributing them, whether patients would use them, and their effectiveness in preventing suicide (20, 21, 41, 43, 45, 46, 51).
Theme 5: Logistical concerns about implementing lethal means safety counseling
Providers, healthcare leaders, and patients reported logistical concerns about implementing LMSC, including provider time constraints, the organization of the healthcare system, and current clinic practices. Providers and patients noted that providers’ time constraints and competing demands serve as barriers to conducting LMSC, particularly if counseling is not brief (21, 22, 41, 43, 45, 47). Providers also described features of the healthcare system and patients’ responses to LMSC that are beyond their control, including limited resources for referrals to mental health care, the potential for legal implications if patients decide not to secure firearms or do so incorrectly, and not being able to ensure that patients followed through on securing firearms (22, 44, 45, 51, 53). Healthcare leaders also noted practical barriers to implementing LMSC, including limited provider time, lack of funding and infrastructure for storing firearms, and clinician turnover (45, 51). On the other hand, providers highlighted potential facilitators to LMSC implementation, including integrating it into clinic workflows, using electronic medical records to prompt providers and monitor implementation, adding provider training to ongoing training opportunities, and having providers aside from doctors (e.g., nurses, medical assistants) deliver LMSC (41, 43–45, 51).
Theme 6: Adapting lethal means safety counseling to individual patients
Patients and providers indicated that LMSC should be adapted to patients’ backgrounds and experiences, including the framing and rationale, asking about firearm access, and recommending storage options (21, 42, 44, 45, 47–52, 54, 55). Relevant patient characteristics included veterans, individuals who live in rural versus urban settings, and women. Veterans wanted providers to acknowledge their expertise with firearms, and those familiar with veterans noted that their camaraderie with one another may make it easier for them to trust other veterans when discussing firearms (42, 47, 48, 51, 52, 54, 55). Patients and providers stated that in some rural communities, firearm ownership is very common, firearms are often used for hunting, and both privacy and the right to own firearms are highly valued (21, 44, 45, 50, 55). In urban settings, on the other hand, some patients may be more likely to own firearms for personal protection (44, 45). A study of female veterans found that many women were familiarized to firearms via men in their lives (54), and another noted that not all patients realize that firearms are a common method of suicide among women (50).
Theme 7: Family members and friends can facilitate lethal means safety counseling
Patients noted that when family members, friends, or others (e.g., a fellow veteran) are trusted, these individuals can facilitate LMSC by helping to remove or store firearms, connecting the patient to care, or initiating conversations about firearm access when the patient is at risk for suicide (42, 43, 46, 51, 52, 54, 55). On the other hand, some family members expressed concern for their own safety when they are put in charge of limiting their loved one’s access to a firearm (51).
Differences across stakeholder groups and clinical settings
When examining differences in subthemes based on stakeholder groups, we found that some subthemes were raised more often by patients than providers. Specifically, patients noted that safety and protection are valued by firearm owners in multiple studies (20, 42, 51, 52, 55), while this was only briefly acknowledged by providers in one study (45). By contrast, the cultural divide regarding firearm-related discussions was raised by providers and patients alike across multiple studies (20, 21, 43–45, 48, 50). Additionally, while patients noted concerns about the quality and cost of firearm storage devices (20, 42), providers did not mention these concerns. We were unable to analyze differences between firearm owners and non-owners, as many studies did not reliably differentiate between these groups. We were also unable to formally analyze differences among various clinical settings as there were insufficient data in each category (emergency departments, adult primary care, and pediatric primary care). We did, however, explore topics specific to pediatric versus adult primary care settings to generate ideas for future research. We found that providers and parents interviewed in the context of pediatric primary care settings were concerned about unintentional injury resulting from youth gaining access to firearms in addition to suicide risk, while those in adult primary care settings focused on suicide risk alone (20, 21, 45, 46). Additionally, as noted in Theme 2, stakeholders in pediatric primary care settings highlighted the value of providers offering advice on safe storage of firearms to all patients as a universal intervention (20, 21, 45) to a greater extent than stakeholders in adult primary care settings, although this view was present to some extent in adult primary care settings as well (47–49).
Medication-related lethal means safety counseling
One paper that examined the potential contributions of community pharmacy teams for suicide prevention in the United Kingdom focused only on medication-related LMSC (40), and two papers that examined both medications and firearms did so within the context of understanding the impact of LMSC training (41) and the development of a firearm and medication storage decision aid (42). The first study (40) highlighted the potential role of pharmacists embedded in the community in identifying patients at risk for suicide and referring them for additional care. While pharmacists rarely mentioned their role in limiting the amount of medication disbursed to at-risk patients, the authors note that further research is needed to examine this issue. Another study (41) described how training in LMSC, as well as the ability to provide medication lockboxes, encouraged providers to counsel parents to remove or lock up medications in the home to limit the risk of overdose among adolescents with behavioral health problems. Finally, the last study (42) noted that decision aids could help patients in the emergency room or other contexts decide how best to store their medications.
Discussion
Our systematic review yielded 19 studies examining stakeholder perceptions of LMSC and its implementation using qualitative methodology. The 18 papers on LMSC related to firearms included a variety of settings (emergency departments, pediatric and adult primary care, and outpatient mental health) and stakeholders (providers, patients, members of the firearm community, healthcare leaders, and community and family members). We identified seven overarching themes that described the meaning and value of firearms to owners’ identities, their views of firearm ownership as a right, and the implications of these views for perceived cultural tensions between patients and providers. While firearm owners were concerned about safety, they were not typically concerned about the risks of unsecured firearms. Additionally, the context in which LMSC was provided and providers’ cultural competency was seen as critical to discussing firearms. Stakeholder recommendations included addressing logistical barriers to LMSC implementation, adapting LMSC to patients’ background and preferences, and potentially involving trusted family members or friends.
Previous reviews have highlighted providers and patients’ hesitancy to engage in LMSC and the importance of provider training, in addition to examining the efficacy of LMSC in changing storage behavior and the ways it is delivered in practice (6, 57–60). As the first review to synthesize findings from qualitative studies on LMSC, the themes we identified provide a more nuanced analysis of the individual and contextual factors that impact LMSC implementation. Analyzing multiple studies also enabled us to identify themes common across different settings and stakeholder groups, and to overcome some of the limitations of individual qualitative studies like small sample sizes. These themes inform clinical, operational and research endeavors aiming to increase the reach and effectiveness of firearm counseling. More specifically, they provide guidance on characteristics of the intervention that may increase acceptability, barriers and facilitators to implementation, and the role of both the clinical setting and larger sociopolitical contexts relevant to discussions about firearm access and storage.
Our review identified several gaps in the LMSC literature that need to be addressed in future research. First, perspectives of various stakeholders, like patients’ family and friends and healthcare leaders, as well as subgroups of individuals (e.g., based on gender, veteran status, geographical location, race/ethnicity, socioeconomic status), were underrepresented in the extant literature. Second, we were unable to differentiate between certain individual characteristics (e.g., firearm owners and non-owners) because studies did not clearly identify participants as such, and the few studies in each clinical setting precluded our analysis of differences across these settings. Third, we found only three studies that explored stakeholders’ perspectives on LMSC for medications and no studies on LMSC for means aside from firearms and medications (e.g., rope). Furthering research in this area is critical, as about half of suicides in the US are not related to firearms. Additionally, rates of death related to poisoning and overdose have risen sharply in recent years, particularly during the COVID-19 pandemic (61). New psychoactive substances like synthetic opioids, which are linked to higher rates of overdose and suicide risk on their own and in combination with medications like benzodiazepines, are also growing in popularity (61, 62). Further qualitative research on LMSC specific to medications and recreational drugs is therefore especially critical at this time. Fourth, only one theme was relevant to the CFIR domain of Process of Implementation and two themes were relevant to Inner Setting, highlighting the limited research relevant to these areas. Notably, the majority of papers included in our review (15 out of 19) were published since 2019, consistent with an uptick in firearm-related research funding and publication nationally (63) and suggesting that some of the gaps in the literature may soon be addressed [e.g., (64)].
This review should be considered alongside several study limitations. First, although the suggestions stemming from this work inform the delivery and implementation of LMSC, most of them have yet to be empirically tested with respect to their acceptability, feasibility, and efficacy. For example, stakeholders reported that emphasizing that changes to firearm storage may be temporary can improve LMSC acceptability. However, we do not know whether temporary changes to storage are effective in preventing suicide nor whether using this language leads to increases in LMSC acceptability. Second, we excluded quantitative studies on LMSC and studies on LMSC effectiveness – while other recent reviews present this research (6, 57–60), these exclusions still limit the scope of our paper. Third, a number of papers we identified were conducted by the same group of investigators within the same parent study – a total of nine published papers stemmed from four parent studies (Table 1). While we analyzed these papers separately because they each included unique groups of participants, this trend further highlights the limited research in this area. Fourth, although we followed guidelines for qualitative syntheses by including only peer-reviewed studies (25, 26), this may have resulted in the exclusion of pertinent studies described in dissertations or other non-peer-reviewed sources. Fifth, some studies in pediatric settings included LMSC for unintentional injury or homicide as well as suicide (20–22) and the extent to which these specific injury outcomes impact perspectives on firearm interventions is unclear. Finally, as in all qualitative syntheses, we aimed to describe a large number of qualitative studies providing in-depth and nuanced information, and were unable to include all relevant data from each study. Therefore, the scope of this synthesis is necessarily constrained to the information we chose to present.
In sum, this study highlights important new findings in the field of LMSC, a rapidly growing field in which understanding and addressing stakeholders’ perceptions is particularly critical (11, 65). Future research should explore the perspectives of patients’ family and friends, healthcare leaders, and subgroups of patients from diverse sociodemographic backgrounds and clinical settings. Additional research is also needed to formally evaluate ways in which stakeholders’ suggestions outlined here impact LMSC effectiveness and implementation.
Data availability statement
The original contributions presented in this study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author.
Author contributions
GK led the study, including study conceptualization, data analysis, and manuscript writing. GK, SK, KH, and JS participated in data analysis. GK, KH, SS, and EM participated in literature reviewing. All authors contributed to manuscript revision, and read and approved the final version.
Funding
JS has provided consulting services to Peraton, which are unrelated to this manuscript. GK was supported by the Office of Academic Affiliations, Advanced Fellowship Program in Mental Illness Research and Treatment, Department of Veterans Affairs. KH was supported by a National Institute of Mental Health Training Fellowship (T32 MH109433; MPI, David S. Mandell, ScD, Rinad S. Beidas). SL was supported by Quality Enhancement Research Initiative (QUERI) grants (PII 18-195; QUE 20-026).
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Author disclaimer
The views expressed in this study are those of the authors and do not necessarily reflect the position or policy of the United States Department of Veterans Affairs (VA), Veterans Health Administration (VHA), or the United States Government.
Supplementary material
The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.993415/full#supplementary-material
References
1. Hedegaard H. Suicide mortality in the united states, 1999–2019. NCHS data brief, no 398. Hyattsville, MD: National Center for Health Statistics (2021). doi: 10.15620/cdc:101761
2. Barber CW, Miller MJ. Reducing a suicidal person’s access to lethal means of suicide. Am J Prev Med. (2014) 47:S264–72. doi: 10.1016/j.amepre.2014.05.028
3. Pallin R, Spitzer SA, Ranney ML, Betz ME, Wintemute GJ. Preventing firearm-related death and injury. Ann Intern Med. (2019) 170:ITC81. doi: 10.7326/AITC201906040
4. Runyan CW, Brooks-Russell A, Tung G, Brandspigel S, Betz ME, Novins DK, et al. Hospital emergency department lethal means counseling for suicidal patients. Am J Prev Med. (2018) 54:259–65. doi: 10.1016/j.amepre.2017.10.023
5. Johnson RM, Frank EM, Ciocca M, Barber CW. Training mental healthcare providers to reduce at-risk Patients’ access to lethal means of suicide: evaluation of the CALM project. Arch Suicide Res. (2011) 15:259–64. doi: 10.1080/13811118.2011.589727
6. Roszko PJD, Ameli J, Carter PM, Cunningham RM, Ranney ML. Clinician attitudes, screening practices, and interventions to reduce firearm-related injury. Epidemiol Rev. (2016) 38:87–110. doi: 10.1093/epirev/mxv005
7. Betz ME, Kautzman M, Segal DL, Miller I, Camargo CA, Boudreaux ED, et al. Frequency of lethal means assessment among emergency department patients with a positive suicide risk screen. Psychiatry Res. (2018) 260:30–5. doi: 10.1016/j.psychres.2017.11.038
8. Noyes J, Booth A, Flemming K, Garside R, Harden A, Lewin S, et al. Cochrane qualitative and implementation methods group guidance series—paper 3: methods for assessing methodological limitations, data extraction and synthesis, and confidence in synthesized qualitative findings. J Clin Epidemiol. (2018) 97:49–58. doi: 10.1016/j.jclinepi.2017.06.020
9. Thomas J, Harden A. Methods for the thematic synthesis of qualitative research in systematic reviews. BMC Med Res Methodol. (2008) 8:45. doi: 10.1186/1471-2288-8-45
10. Harris JL, Booth A, Cargo M, Hannes K, Harden A, Flemming K, et al. Cochrane qualitative and implementation methods group guidance series—paper 2: methods for question formulation, searching, and protocol development for qualitative evidence synthesis. J Clin Epidemiol. (2018) 97:39–48. doi: 10.1016/j.jclinepi.2017.10.023
11. Betz ME, Anestis MD. Firearms, pesticides, and suicide: a look back for a way forward. Prev Med. (2020) 138:106144. doi: 10.1016/j.ypmed.2020.106144
12. Simonetti JA, Brenner LA. Promoting firearm safety as a suicide prevention strategy within health care systems: challenges and recommendations. Psychiatr Serv. (2020) 71:298–300. doi: 10.1176/appi.ps.201900286
13. Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. (2009) 4:50. doi: 10.1186/1748-5908-4-50
14. Tong A, Flemming K, McInnes E, Oliver S, Craig J. Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med Res Methodol. (2012) 12:181. doi: 10.1186/1471-2288-12-181
15. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. (2021) 9:n71. doi: 10.1136/bmj.n71
16. Hadegaard H, Bastian BA, Trinidad JP, Spencer M, Warner M. Drugs most frequently involved in drug overdose deaths: united states, 2011-2016. Natl Vital Stat Rep. (2018) 67:1–13.
17. Bjornestad J, Lavik KO, Davidson L, Hjeltnes A, Moltu C, Veseth M. Antipsychotic treatment – a systematic literature review and meta-analysis of qualitative studies. J Ment Health. (2020) 29:513–23. doi: 10.1080/09638237.2019.1581352
18. Levitt HM, Pomerville A, Surace FI. A qualitative meta-analysis examining clients’ experiences of psychotherapy: a new agenda. Psychol Bull. (2016) 142:801–30. doi: 10.1037/bul0000057
19. Abdallah HO, Kaufman EJ. Before the bullets fly: the physician’s role in preventing firearm injury. Yale J Biol Med. (2021) 94:147–52.
20. Aitken ME, Minster SD, Mullins SH, Hirsch HM, Unni P, Monroe K, et al. Parents’ perspectives on safe storage of firearms. J Community Health. (2020) 45:469–77. doi: 10.1007/s10900-019-00762-2
21. Hinnant A, Boman CD, Hu S, Ashley RR, Lee S, Dodd S, et al. The third rail of pediatric communication: discussing firearm risk and safety in well-child exams. Health Commun. (2021) 36:508–20. doi: 10.1080/10410236.2019.1700883
22. Barkin S, Ryan G, Gelberg L. What pediatricians can do to further youth violence prevention–a qualitative study. Inj Prev. (1999) 5:53–8. doi: 10.1136/ip.5.1.53
23. Sandelowski M, Barroso J. Handbook for synthesizing qualitative research. New York: Springer (2010).
24. Booth A, Noyes J, Flemming K, Gerhardus A, Wahlster P, van der Wilt G, et al. Guidance on Choosing Qualitative Evidence Synthesis Methods for Use in Health Technology Assessments of Complex Interventions. (2016). Available online at: http://www.integrate-hta.eu/downloads/ (accessed September 2022).
25. Levitt HM. How to conduct a qualitative meta-analysis: tailoring methods to enhance methodological integrity. Psychother Res. (2018) 28:367–78. doi: 10.1080/10503307.2018.1447708
26. Timulak L. Meta-analysis of qualitative studies: a tool for reviewing qualitative research findings in psychotherapy. Psychother Res. (2009) 19:591–600. doi: 10.1080/10503300802477989
27. Haught K, Grossman D, Connell F. Parents’ attitudes toward firearm injury prevention counseling in urban pediatric clinics. Pediatrics. (1995) 96:649–53. doi: 10.1542/peds.96.4.649
28. Marino E, Wolsko C, Keys SG, Pennavaria L. A culture gap in the United States: implications for policy on limiting access to firearms for suicidal persons. J Public Health Policy. (2016) 37:110–21. doi: 10.1057/s41271-016-0007-2
29. Kalesan B, Villarreal MD, Keyes KM, Galea S. Gun ownership and social gun culture. Inj Prev. (2016) 22(3):216–20. doi: 10.1136/injuryprev-2015-041586
30. CASP. Qualitative Appraisal Checklist for Qualitative Research. (2011). Available online at: http://www.casp-uk.net/#!casp-tools-checklists/c18f8 (accessed September 2022).
31. Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. (2007) 19:349–57. doi: 10.1093/intqhc/mzm042
32. Lewin S, Booth A, Glenton C, Munthe-Kaas H, Rashidian A, Wainwright M, et al. Applying GRADE-CERQual to qualitative evidence synthesis findings: introduction to the series. Implement Sci. (2018) 2:13012. doi: 10.1186/s13012-017-0688-3
33. Tufford L, Newman P. Bracketing in qualitative research. Qual Soc Work. (2012) 11:80–96. doi: 10.1177/1473325010368316
34. Ryan C, Hesselgreaves H, Wu O, Paul J, Dixon-Hughes J, Moss JG. Protocol for a systematic review and thematic synthesis of patient experiences of central venous access devices in anti-cancer treatment. Syst Rev. (2018) 7:61. doi: 10.1186/s13643-018-0721-x
35. Devan H, Hale L, Hempel D, Saipe B, Perry MA. What works and does not work in a self-management intervention for people with chronic pain? Qualit Syst Rev Meta Synthe Phys Ther. (2018) 98:381–97. doi: 10.1093/ptj/pzy029
36. Mackenzie K, Such E, Norman P, Goyder E. The development, implementation and evaluation of interventions to reduce workplace sitting: a qualitative systematic review and evidence-based operational framework. BMC Public Health. (2018) 18:833. doi: 10.1186/s12889-018-5768-z
37. Barnett-Page E, Thomas J. Methods for the synthesis of qualitative research: a critical review. BMC Med Res Methodol. (2009) 9:59. doi: 10.1186/1471-2288-9-59
38. Safaeinili N, Brown-Johnson C, Shaw JG, Mahoney M, Winget M. CFIR simplified: pragmatic application of and adaptations to the consolidated framework for implementation research (CFIR) for evaluation of a patient-centered care transformation within a learning health system. Learn Health Syst. (2020) 4:10201. doi: 10.1002/lrh2.10201
39. Hoyt T, Holliday R, Simonetti JA, Monteith LL. Firearm lethal means safety with military personnel and veterans: overcoming barriers using a collaborative approach. Prof Psychol Res Pract. (2021) 52:387–95. doi: 10.1037/pro0000372
40. Gorton HC, Littlewood D, Lotfallah C, Spreadbury M, Wong KL, Gooding P, et al. Current and potential contributions of community pharmacy teams to self-harm and suicide prevention: a qualitative interview study. PLoS One. (2019) 14:e0222132. doi: 10.1371/journal.pone.0222132
41. Salhi C, Berrigan J, Azrael D, Beatriz E, Barber C, Runyan C, et al. “It’s changed how we have these conversations”: emergency department clinicians’ experiences implementing firearms and other lethal suicide methods counseling for caregivers of adolescents. Int Rev Psychiatry. (2021) 33:617–25. doi: 10.1080/09540261.2020.1870938
42. Siry B, Knoepke C, Ernestus S, Matlock D, Betz M. Lethal means counseling for suicidal adults in the emergency department: a qualitative study. West J Emerg Med. (2021) 22:9. doi: 10.5811/westjem.2021.8.49485
43. Siry B, Polzer E, Omeragic F, Knoepke CE, Matlock DD, Betz ME. Lethal means counseling for suicide prevention: views of emergency department clinicians. Gen Hosp Psychiatry. (2021) 71:95–101. doi: 10.1016/j.genhosppsych.2021.04.011
44. Wolf LA, Delao AM, Perhats C, Clark PR, Moon MD, Zavotsky KE, et al. Emergency Nurses’ perceptions of risk for firearm injury and its effect on assessment practices: a mixed methods study. J Emerg Nurs. (2019) 45:54–66.e2. doi: 10.1016/j.jen.2018.09.010
45. Benjamin Wolk C, Van Pelt AE, Jager-Hyman S, Ahmedani BK, Zeber JE, Fein JA, et al. Stakeholder perspectives on implementing a firearm safety intervention in pediatric primary care as a universal suicide prevention strategy: a qualitative study. JAMA Netw Open. (2018) 1:e185309. doi: 10.1001/jamanetworkopen.2018.5309
46. Jager-Hyman S, Benjamin Wolk C, Ahmedani BK, Zeber JE, Fein JA, Brown GK, et al. Perspectives from firearm stakeholders on firearm safety promotion in pediatric primary care as a suicide prevention strategy: a qualitative study. J Behav Med. (2019) 42:691–701. doi: 10.1007/s10865-019-00074-9
47. Dobscha SK, Clark KD, Newell S, Kenyon EA, Karras E, Simonetti JA, et al. Strategies for discussing firearms storage safety in primary care: veteran perspectives. J Gen Intern Med. (2021) 36:1492–502. doi: 10.1007/s11606-020-06412-x
48. Newell S, Kenyon E, Clark KD, Elliott V, Rynerson A, Gerrity MS, et al. Veterans are agreeable to discussions about firearms safety in primary care. J Am Board Fam Med. (2021) 34:338–45. doi: 10.3122/jabfm.2021.02.200261
49. Richards JE, Hohl SD, Segal CD, Grossman DC, Lee AK, Whiteside U, et al. What will happen if i say yes?” Perspectives on a standardized firearm access question among adults with depressive symptoms. Psychiatr Serv. (2021) 72:898–904. doi: 10.1176/appi.ps.202000187
50. Slovak K, Singer JB. Engaging parents of suicidal youth in a rural environment: engaging parents of suicidal youth. Child Fam Soc Work. (2012) 17:212–21. doi: 10.1111/j.1365-2206.2012.00826.x
51. Walters H, Kulkarni M, Forman J, Roeder K, Travis J, Valenstein M. Feasibility and acceptability of interventions to delay gun access in VA mental health settings. Gen Hosp Psychiatry. (2012) 34:692–8. doi: 10.1016/j.genhosppsych.2012.07.012
52. Pallin R, Siry B, Azrael D, Knoepke CE, Matlock DD, Clement A, et al. “Hey, let me hold your guns for a while”: a qualitative study of messaging for firearm suicide prevention. Behav Sci Law. (2019) 37:259–69. doi: 10.1002/bsl.2393
53. Slovak K, Pope N, Giger J, Kheibari A. An evaluation of the counseling on access to lethal means (calm) training with an area agency on aging. J Gerontol Soc Work. (2019) 62:48–66. doi: 10.1080/01634372.2018.1522410
54. Monteith LL, Holliday R, Dorsey Holliman BA, Brenner LA, Simonetti JA. Understanding female veterans’ experiences and perspectives of firearms. J Clin Psychol. (2020) 76:1736–53. doi: 10.1002/jclp.22952
55. Simonetti JA, Dorsey Holliman B, Holiday R, Brenner LA, Monteith LL. Firearm-related experiences and perceptions among United States male veterans: a qualitative interview study. PLoS One. (2020) 15:e0230135. doi: 10.1371/journal.pone.0230135
56. Harvey J, Dopson S, McManus RJ, Powell J. Factors influencing the adoption of self-management solutions: an interpretive synthesis of the literature on stakeholder experiences. Implement Sci. (2015) 10:159. doi: 10.1186/s13012-015-0350-x
57. Rowhani-Rahbar A, Simonetti JA, Rivara FP. Effectiveness of interventions to promote safe firearm storage. Epidemiol Rev. (2016) 3:mxv006. doi: 10.1093/epirev/mxv006
58. Hunter AA, DiVietro S, Boyer M, Burnham K, Chenard D, Rogers SC. The practice of lethal means restriction counseling in US emergency departments to reduce suicide risk: a systematic review of the literature. Inj Epidemiol. (2021) 8:54. doi: 10.1186/s40621-021-00347-5
59. Zalsman G, Hawton K, Wasserman D, van Heeringen K, Arensman E, Sarchiapone M, et al. Suicide prevention strategies revisited: 10-year systematic review. Lancet Psychiatry. (2016) 3:646–59. doi: 10.1016/S2215-0366(16)30030-X
60. McGee KS. Review of evaluations of educational approaches to promote safe storage of firearms. Inj Prev. (2003) 9:108–11. doi: 10.1136/ip.9.2.108
61. Friedman JR, Hansen H. Evaluation of increases in drug overdose mortality rates in the US by race and ethnicity before and during the COVID-19 pandemic. JAMA Psychiatry. (2022) 79:379. doi: 10.1001/jamapsychiatry.2022.0004
62. Chiappini S, Mosca A, Miuli A, Santovito MC, Orsolini L, Corkery JM, et al. New psychoactive substances and suicidality: a systematic review of the current literature. Medicina. (2021) 57:580. doi: 10.3390/medicina57060580
63. Subbaraman N. Gun violence is surging — researchers finally have the money to ask why. Nature. (2021) 595:486–8. doi: 10.1038/d41586-021-01966-0
64. Thomas AC, Siry-Bove BJ, Barnard LM, Rooney L, McCarthy M, Mustafa A, et al. A qualitative study on diverse perspectives and identities of firearm owners. Inj Prev. (2022) 24:522. doi: 10.1136/injuryprev-2022-044522
Keywords: suicide, lethal means, firearms, medications, qualitative, thematic synthesis, implementation, CFIR
Citation: Khazanov GK, Keddem S, Hoskins K, Myhre K, Sullivan S, Mitchell E, Holliman BD, Landes SJ and Simonetti J (2022) Stakeholder perceptions of lethal means safety counseling: A qualitative systematic review. Front. Psychiatry 13:993415. doi: 10.3389/fpsyt.2022.993415
Received: 13 July 2022; Accepted: 29 September 2022;
Published: 20 October 2022.
Edited by:
Domenico De Berardis, Mental Health Center (CSM) and Psychiatric Service of Diagnosis and Treatment (SPDC), ItalyReviewed by:
Julie Richards, Kaiser Permanente Washington Health Research Institute, United StatesAndrea Miuli, University of Studies G. d’Annunzio Chieti and Pescara, Italy
Copyright © 2022 Khazanov, Keddem, Hoskins, Myhre, Sullivan, Mitchell, Holliman, Landes and Simonetti. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Gabriela Kattan Khazanov, gabriela.khazanov@va.gov