AUTHOR=Kwon Hye-Young , Kim Yongjoo , Lee Seung-Young TITLE=What Matters for Depression and Anxiety During the COVID-19 Quarantine?: Results of an Online Cross-Sectional Survey in Seoul, South Korea JOURNAL=Frontiers in Psychiatry VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.706436 DOI=10.3389/fpsyt.2022.706436 ISSN=1664-0640 ABSTRACT=Background

Amid the COVID-19 pandemic, quarantine measures are key to containing the spread of the virus. Millions of people have been required to quarantine throughout the pandemic; the quarantine itself is considered detrimental to mental health conditions.

Objective

This study aims to investigate the factors associated with depression and anxiety among quarantined people in Seoul, South Korea.

Methods

An online cross-sectional survey was administered from October to November 2020 involving people who were living in Seoul, aged 19 years or above, under a 2-week mandatory quarantine. Their mental health status was measured using the Patient Health Questionnares-9 (PHQ-9) and the General Anxiety Disorder-7 (GAD-7).

Results

Overall, 1,135 respondents were finally included, resulting in a 22.0% response rate. After controlling for potential confounders, variables, such as the “second half of quarantine period” (OR = 1.78 95% CI: 1.10–2.88), “female” (OR = 1.91 95% CI: 1.16–3.16), and “having pre-existing depression” (OR = 8.03 95% CI: 2.96–21.78) were significantly associated with depression while being quarantined. Those with correct knowledge about the rationale behind for the quarantine (OR = 0.39 95% CI: 0.21–0.72), an understanding of quarantine rules (OR = 0.68 95%CI: 0.52–0.91), and those who felt supported by others (OR = 0.74 95% CI: 0.55–0.99) were less likely to develop depression while quarantining. Similarly, anxiety was significantly associated with the second week (OR = 4.18 95% CI: 1.44–12.09), those with an unstable job status (OR = 3.95 95% CI: 1.60–9.79), perceived support (OR = 0.66, 95% CI: 0.45–0.96), and the fear of being infected (OR = 7.22 95% CI: 1.04–49.95).

Conclusions

This study highlights the need to develop precautionary measures to prevent depression and anxiety among people undergoing COVID-19 quarantine. In particular, individuals with depression prior to quarantine should be carefully monitored during the quarantine. Further studies with larger populations are needed.