AUTHOR=Wang Qiang , Zhang Lei , Zhang Jiechun , Ye Zhihao , Li Ping , Wang Feng , Cao Yili , Zhang Shaojun , Zhou Fang , Ai Zisheng , Zhao Nan 

TITLE=Prevalence of Comorbid Personality Disorder in Psychotic and Non-psychotic Disorders

JOURNAL=Frontiers in Psychiatry

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2021.800047

DOI=10.3389/fpsyt.2021.800047

ISSN=1664-0640

ABSTRACT=<p><bold>Introduction:</bold> The burden of personality disorders (PDs) in China is large and the focus on mental health services is increasing. However, there is a lack of sufficient evidence regarding the prevalence of comorbid PD in psychotic and non-psychotic disorders, and whether PDs have different distributions. We aimed to investigate the PD comorbidity distribution pattern between psychotic and non-psychotic disorders using a clinical population-based study.</p><p><bold>Materials and Methods:</bold> We conducted a cross-sectional study of 1,497 patients in Shanghai. PDs were screened using the Personality Diagnostic Questionnaire Fourth Edition Plus (PDQ-4+). All patients were interviewed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) Axis II (SCID-II). We compared the differences in PD comorbidities classified as the 10 types of PDs in the DSM-IV, in 531 patients with psychosis and 966 patients with non-psychotic disorders.</p><p><bold>Results:</bold> More than one-third (37%) of patients with psychotic disorders met the criteria of at least one PD. Approximately half (46%) of patients with non-psychotic disorders met the criteria of at least one PD. Patients with non-psychotic disorders were more likely to meet the criteria of borderline (χ<sup>2</sup> = 20.154, <italic>p</italic> &lt; 0.001) and obsessive-compulsive PD (χ<sup>2</sup> = 21.164, <italic>p</italic> &lt; 0.001) diagnoses compared to those with psychotic disorders. In contrast, patients with psychotic disorders were more likely to meet the criteria of paranoid (χ<sup>2</sup> = 11.144, <italic>p</italic> = 0.001) and schizotypal PD (χ<sup>2</sup> = 14.004, <italic>p</italic> &lt; 0.001) diagnoses than those with non-psychotic disorders.</p><p><bold>Discussion:</bold> PD comorbidity is common and comorbidity distribution pattern is varied in patients with psychotic and non-psychotic disorders, implicating the development of specific strategies that could screen and assess PDs in psychiatric clinical practice.</p>