AUTHOR=Stelmach Ewa , Masiak Jolanta 

TITLE=Case Report: Psychopathological Syndromes in the Course of Lupus Erythematosus and the Co-occurrence of Lupus Erythematous With Mental Disorders

JOURNAL=Frontiers in Psychiatry

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2021.668050

DOI=10.3389/fpsyt.2021.668050

ISSN=1664-0640

ABSTRACT=<p><bold>Background:</bold> Systemic lupus erythematosus (SLE) is an autoimmune disease that leads to a chronic inflammatory process in tissues and organs. The neuropsychiatric systemic lupus erythematosus (NPSLE) is a set of neuropsychiatric symptoms that derive from the central and peripheral nervous system and are observed in the course of SLE.</p><p><bold>Case Report and Final Diagnostic and Therapeutic Results:</bold> A diagnostic and therapeutic process in a patient with the signs and symptoms of SLE and bipolar disorder (BD) has been described. Bipolar disorder has been diagnosed as a primary disorder while SLE as a comorbid disease.</p><p><bold>Discussion:</bold> Common immunological mechanisms in BD and SLE are the reason for difficulties in diagnosing BD with co-occurring SLE. It should be determined whether BD is a primary disorder or a secondary component of a clinical picture of SLE (NPSLE) or whether mood and/or psychotic disorders are the result of steroid therapy in the course of SLE (steroid-induced mood and psychotic disorders, SIMPD).</p><p><bold>Conclusion and the Patient's Perspective:</bold> The presented case report is a unique description of a patient with a primary diagnosis of BD with comorbid SLE.</p>