AUTHOR=Ou Wenwen , Li Zhijun , Zheng Qi , Chen Wentao , Liu Jin , Liu Bangshan , Zhang Yan 

TITLE=Association Between Childhood Maltreatment and Symptoms of Obsessive-Compulsive Disorder: A Meta-Analysis

JOURNAL=Frontiers in Psychiatry

VOLUME=11

YEAR=2021

URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2020.612586

DOI=10.3389/fpsyt.2020.612586

ISSN=1664-0640

ABSTRACT=<p><bold>Background:</bold> Previous studies have indicated that childhood maltreatment (CM) may potentially influence the clinical symptomatology of obsessive-compulsive disorder (OCD). Here, we aimed to quantify the relationship between CM and obsessive-compulsive symptoms (OCS) and depressive symptoms in OCD through a meta-analysis.</p><p><bold>Method:</bold> We searched PubMed, Embase, Cochrane Library, and PsycARTICLES databases for articles reporting the association between CM and OCD on April 15, 2020. Random-effect models were used to quantify the relationship between CM and the severity of OCS and depressive symptoms in OCD.</p><p><bold>Results:</bold> Ten records with 1,611 OCD patients were included in the meta-analysis. The results revealed that CM is positively correlated with the severity of OCS [<italic>r</italic> = 0.10, 95%Confidence Interval (CI): 0.01–0.19, <italic>P</italic> = 0.04] as well as depressive symptoms in OCD (<italic>r</italic> = 0.15, 95%CI: 0.07–0.24, <italic>P</italic> = 0.0002). For the subtypes of CM, childhood emotional abuse (CEA) and childhood sexual abuse (CSA) was related with the severity of OCS (<italic>r</italic> = 0.11, 95%CI: 0.03–0.19, <italic>P</italic> = 0.009) and obsession (<italic>r</italic> = 0.13, 95%CI: 0.03–0.23, <italic>P</italic> = 0.01), respectively.</p><p><bold>Conclusion:</bold> Our meta-analysis indicates that OCD patients who suffered more CM may exhibit more severe OCS and depressive symptoms.</p>