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ORIGINAL RESEARCH article
Front. Plant Sci.
Sec. Plant Metabolism and Chemodiversity
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1558321
This article is part of the Research TopicPlant Natural Products: Biosynthesis, Regulation, and FunctionView all 15 articles
Genome-wide analysis of MYB transcription factors in four Rheum L. plants provides new insights into the synthesis of AQs
Provisionally accepted
Tao WANG1,2
Shuo Zhao1,2
Bo Wang1,2Jianan Li1,2Zengrong Ye1,3Famei Zhang1,2Huiyuan Ma1,4
Guoying Zhou1,2*- 1Northwest Institute of Plateau Biology, Chinese Academy of Sciences (CAS), Xining, Qinghai Province, China
- 2University of Chinese Academy of Sciences, Beijing, China
- 3Qinghai University, Xining, Qinghai Province, China
- 4Qinghai Normal University, Xining, Qinghai Province, China
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R. tanguticum (Rheum tanguticum Maxim. ex Regel) is a herbaceous plant belonging to Polygonaceae family and Rheum L. genus. It holds considerable value in culinary and medicinal realms, primarily due to their rich AQs content. Understanding the molecular mechanisms that regulate AQs biosynthesis is a prerequisite for increasing their yield. MYB transcription factors (TFs) can regulate the synthesis of a variety of plant secondary metabolites. However, only a few research have explored the role of MYB TFs in Rheum L. species. In this study, 1054 MYB genes from four Rheum L. species were identified. The number of MYB genes in each species was similar, distributed across 11 chromosomes. To investigate the phylogeny of identified MYB TFs, they were classified into four subfamilies. Sequence characteristics, phylogenetic relationships, evolutionary trends, and tissue expression of MYB genes in Rheum L. species were further studied. Subsequently, 12 MYB genes were selected, which shown differential expression in different tissues. Further research on these genes indicated a significant correlation with genes in shikimate pathway and polyketide pathway of AQs biosynthesis. Protein-protein interaction simulations in Arabidopsis thaliana and qRT-PCR experiments further confirmed this situation. This research lays the foundation for studying molecular mechanisms by which MYB TFs regulates AQs biosynthesis in four Rheum L. species.
Keywords: MYBs, AQS, Genome-wide analysis, RNA-Seq, qPCR, Rheum L. Plants
Received: 10 Jan 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 WANG, Zhao, Wang, Li, Ye, Zhang, Ma and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guoying Zhou, Northwest Institute of Plateau Biology, Chinese Academy of Sciences (CAS), Xining, 810008, Qinghai Province, China
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