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ORIGINAL RESEARCH article
Front. Plant Sci.
Sec. Plant Biotechnology
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1554216
Genome Wide Association Study of Seedling-Plant Resistance to Stripe Rust in Bread Wheat (Triticum aestivum L.) Genotypes
Provisionally accepted
Genet Atsbeha Fiseha 1*
Tilahun Mekonnen 2*
Haftom Brhane Mesfin 3*
Mulugeta Kebede 2
Teklehaimanot Haileselassie 2
Kassahun Tesfaye (PhD) 2- 1 Adama Science and Technology University, Adama, Ethiopia
- 2 Addis Ababa University, Addis Ababa, Addis Ababa, Ethiopia
- 3 Plant breeding department, Alnarp, Swedish University of Agricultural Sciences, Uppsala, Uppsala, Sweden
Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. To enhance Ethiopian wheat production, incorporating genetically resistant cultivars into breeding programs is essential.Accordingly, this study aimed at exploring the genome-wide association of seedling resistance in 178 wheat genotypes to identify genetic markers linked to yellow rust resistance. The panel was phenotyped for yellow rust seedling resistance at Kulumsa Agricultural Research Centre Pathology Laboratory. Additionally, the association panel was genotyped using the genotypingby-sequencing (GBS) platform and a total of 6,788 polymorphic SNPs were used in genomewide association analysis to identify effective yellow rust resistance genes. The genome association and prediction integrated tool (GAPIT) was used to analyze marker-trait associations.The overall linkage disequilibrium (LD) decreased within an average physical distance of 31.44 Mbp at r 2 = 0.2. Marker trait associations (MTA) analysis revealed 102 loci that are significantly (p = 0.001) related to yellow rust seedling-plant resistance. The majority of the discovered resistance quantitative trait loci (QTLs) were located on the same chromosomes as previously reported QTLs for yellow rust resistance, specifically on chromosomes 1A,
Keywords: Genetic architecture, Linkage Disequilibrium, SNP markers, Marker trait association, novel loci, Puccinia striiformis
Received: 01 Jan 2025; Accepted: 07 Apr 2025.
Copyright: © 2025 Fiseha, Mekonnen, Mesfin, Kebede, Haileselassie and Tesfaye (PhD). This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Genet Atsbeha Fiseha, Adama Science and Technology University, Adama, Ethiopia
Tilahun Mekonnen, Addis Ababa University, Addis Ababa, Addis Ababa, Ethiopia
Haftom Brhane Mesfin, Plant breeding department, Alnarp, Swedish University of Agricultural Sciences, Uppsala, 75651, Uppsala, Sweden
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