AUTHOR=Bresnahan Kristin A. , Ferber Justin M. , Carrato J. Thomas , Stoddard Thomas J. , Palad Patrick V. , Richani Magi TITLE=Closed-loop systems for plants expressing animal proteins: a modernized framework to safeguard the future of agricultural innovation JOURNAL=Frontiers in Plant Science VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2025.1426290 DOI=10.3389/fpls.2025.1426290 ISSN=1664-462X