AUTHOR=Ma Xiaoran , Liang Qingwei , Han Yusi , Fan Lu , Yi Dengxia , Ma Lin , Tang Jun , Wang Xuemin 

TITLE=Integrated transcriptomic, proteomic and metabolomic analyses revealing the roles of amino acid and sucrose metabolism in augmenting drought tolerance in Agropyron mongolicum

JOURNAL=Frontiers in Plant Science

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2024.1515944

DOI=10.3389/fpls.2024.1515944

ISSN=1664-462X

ABSTRACT=<p>Drought, a major consequence of climate change, initiates molecular interactions among genes, proteins, and metabolites. <italic>Agropyron mongolicum</italic> a high-quality perennial grass species, exhibits robust drought resistance. However, the molecular mechanism underlying this resistance remaining largely unexplored. In this study, we performed an integrated analysis of the transcriptome, proteome, and metabolome of <italic>A. mongolicum</italic> under optimal and drought stress conditions. This combined analysis highlighted the pivotal role of transporters in responding to drought stress. Moreover, metabolite profiling indicated that arginine and proline metabolism, as well as the pentose phosphate pathway, are significantly involved in the drought response of <italic>A. mongolicum</italic>. Additionally, the integrated analysis suggested that proline metabolism and the pentose phosphate pathway are key elements of the drought resistance strategy in <italic>A. mongolicum</italic> plants. In summary, our research elucidates the drought adaptation mechanisms of <italic>A. mongolicum</italic> and identifies potential candidate genes for further study.</p>