AUTHOR=Caccamo Anna , Lazzarotto Fernanda , Margis-Pinheiro Marcia , Messens Joris , Remacle Claire 

TITLE=The ascorbate peroxidase–related protein: insights into its functioning in Chlamydomonas and Arabidopsis

JOURNAL=Frontiers in Plant Science

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2024.1487328

DOI=10.3389/fpls.2024.1487328

ISSN=1664-462X

ABSTRACT=<p>We review the newly classified ascorbate peroxidase–related (APX-R) proteins, which do not use ascorbate as electron donor to scavenge H<sub>2</sub>O<sub>2</sub>. We summarize recent discoveries on the function and the characterization of the APX-R protein of the green unicellular alga <italic>Chlamydomonas reinhardtii</italic> and the land plant <italic>Arabidopsis thaliana</italic>. Additionally, we conduct <italic>in silico</italic> analyses on the conserved MxxM motif, present in most of the APX-R protein in different organisms, which is proposed to bind copper. Based on these analyses, we discuss the similarities between the APX-R and the class III peroxidases.</p>