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ORIGINAL RESEARCH article

Front. Plant Sci.
Sec. Plant Pathogen Interactions
Volume 15 - 2024 | doi: 10.3389/fpls.2024.1482934

The nucleolin MoNsr1 plays pleiotropic roles in the pathogenicity and stress adaptation in the rice blast fungus Magnaporthe oryzae

Provisionally accepted
Zhen Zhang Zhen Zhang 1Mohammad S. Islam Mohammad S. Islam 1,2Jiuzhi Xia Jiuzhi Xia 1Xiangyang Feng Xiangyang Feng 1Muhammad Noman Muhammad Noman 1,3,4Jing Wang Jing Wang 1Zhongna Hao Zhongna Hao 1Haiping Qiu Haiping Qiu 1Rongyao Chai Rongyao Chai 1Yingying Cai Yingying Cai 1Yanli Wang Yanli Wang 1Jiaoyu Wang Jiaoyu Wang 1*
  • 1 Zhejiang Academy of Agricultural Sciences, Hangzhou, China
  • 2 Zhejiang University, Hangzhou, Zhejiang Province, China
  • 3 European University of Lefka, Lefka, Türkiye
  • 4 Western Caspian University, Baku, Azerbaijan

The final, formatted version of the article will be published soon.

    The rice blast disease, caused by the fungus Magnaporthe oryzae, is a significant agricultural problem that adversely impacts rice production and food security.Understanding the precise molecular pathways involved in the interaction between the pathogen and its host is crucial for developing effective disease management strategies. This study examines the crucial function of the nucleolin MoNsr1 in regulating M. oryzae physiological functions. ΔMoNsr1 deletion mutants showed reduced fungal growth, asexual sporulation, and pathogenicity compared to the wildtype. Mutants exhibited impaired conidial germination and appressoria formation, reducing infection progression. Additionally, ΔMoNsr1 deletion mutant had less turgor pressure, confirming that MoNsr1 is essential for cell wall biogenesis and resistant to external stresses. Furthermore, ΔMoNsr1 deletion mutant showed enhanced sensitivity to oxidative stress, reactive oxygen species, and cold tolerance.Our results offer a thorough understanding of the function of MoNsr1 in the virulence and stress-resilient capability in M. oryzae. These findings provide insights into the novel targets and contribute to the emergence of innovative approaches for managing rice blast disease.

    Keywords: cell wall integrity, Magnaporthe oryzae, MoNsr1, nucleolin, pathogenicity, stress response

    Received: 22 Aug 2024; Accepted: 23 Sep 2024.

    Copyright: © 2024 Zhang, Islam, Xia, Feng, Noman, Wang, Hao, Qiu, Chai, Cai, Wang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jiaoyu Wang, Zhejiang Academy of Agricultural Sciences, Hangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.