AUTHOR=Faye Loïc , Grünwald-Gruber Clemens , Vezina Louis-Philippe , Gomord Véronique , Morel Bertrand 

TITLE=A fast and easy one-step purification strategy for plant-made antibodies using Protein A magnetic beads

JOURNAL=Frontiers in Plant Science

VOLUME=14

YEAR=2024

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2023.1276148

DOI=10.3389/fpls.2023.1276148

ISSN=1664-462X

ABSTRACT=<p>A major difficulty to reach commercial- scale production for plant-made antibodies is the complexity and cost of their purification from plant extracts. Here, using Protein A magnetic beads, two monoclonal antibodies are purified in a one-step procedure directly from non-clarified crude plant extracts. This technique provides significant savings in terms of resources, operation time, and equipment.</p>