AUTHOR=Riemer Esther , Pullagurla Naga Jyothi , Yadav Ranjana , Rana Priyanshi , Jessen Henning J. , Kamleitner Marília , Schaaf Gabriel , Laha Debabrata 

TITLE=Regulation of plant biotic interactions and abiotic stress responses by inositol polyphosphates

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.944515

DOI=10.3389/fpls.2022.944515

ISSN=1664-462X

ABSTRACT=<p>Inositol pyrophosphates (PP-InsPs), derivatives of inositol hexakisphosphate (phytic acid, InsP<sub>6</sub>) or lower inositol polyphosphates, are energy-rich signaling molecules that have critical regulatory functions in eukaryotes. In plants, the biosynthesis and the cellular targets of these messengers are not fully understood. This is because, in part, plants do not possess canonical InsP<sub>6</sub> kinases and are able to synthesize PP-InsP isomers that appear to be absent in yeast or mammalian cells. This review will shed light on recent discoveries in the biosynthesis of these enigmatic messengers and on how they regulate important physiological processes in response to abiotic and biotic stresses in plants.</p>