AUTHOR=Strasser Richard 

TITLE=Recent Developments in Deciphering the Biological Role of Plant Complex N-Glycans

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.897549

DOI=10.3389/fpls.2022.897549

ISSN=1664-462X

ABSTRACT=<p>Asparagine (<italic>N</italic>)-linked protein glycosylation is a ubiquitous co- and posttranslational modification which has a huge impact on the biogenesis and function of proteins and consequently on the development, growth, and physiology of organisms. In mammals, <italic>N</italic>-glycan processing carried out by Golgi-resident glycosidases and glycosyltransferases creates a number of structurally diverse <italic>N</italic>-glycans with specific roles in many different biological processes. In plants, complex <italic>N</italic>-glycan modifications like the attachment of β1,2-xylose, core α1,3-fucose, or the Lewis A-type structures are evolutionary highly conserved, but their biological function is poorly known. Here, I highlight recent developments that contribute to a better understanding of these conserved glycoprotein modifications and discuss future directions to move the field forward.</p>