AUTHOR=Chen Jia-Hui , Hou Na , Xv Xv , Zhang Da , Fan Tong-Qiang , Zhang Qi-Xiang , Huang You-Jun 

TITLE=Flavonoid Synthesis and Metabolism During the Fruit Development in Hickory (Carya cathayensis)

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.896421

DOI=10.3389/fpls.2022.896421

ISSN=1664-462X

ABSTRACT=<p>Hickory (<italic>Carya cathayensis</italic>) kernel is rich in powerful bioactive flavonoids, which can remove excess free radicals in the human body and play an important role in regulating the physiological metabolism of the plant. This study investigated the changes of flavonoids in hickory exocarp and embryo during development. In this study, 72 DEGs involved in the regulation of flavonoid biosynthesis in fruits were identified, and <italic>TT4</italic>, <italic>CCoAOMT1</italic>, <italic>UGT71D1</italic>, <italic>C4H</italic>, <italic>F3H</italic>, <italic>TT8</italic>, <italic>FLS1</italic>, and <italic>LDOX</italic> were identified as the core genes of flavonoid biosynthesis. A total of 144 flavonoid-related metabolites were detected by metabolite analysis. Transcriptome and metabolome analysis combined to construct the flavonoid biosynthesis regulatory pathway in the development stage of hickory fruit. Our results provide a theoretical basis for the exploration and regulation of functional genes related to flavonoid biosynthesis and metabolism in hickory and other plants and the breeding of new walnut varieties.</p>