AUTHOR=Lin Yuan , Hao Bing , Lu Ying Chun , Dong Yang , Li Ying , Zhang Guang Hui , Yang Zi Jiang , Xiang Gui Sheng , Liu Guan Ze , Li Xue Jiao , Zhu Qin , Yang Qing Hui , Li Xu Zhen , Yang Sheng Chao 

TITLE=PanaxGDB: A Comprehensive Platform for Panax

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.883818

DOI=10.3389/fpls.2022.883818

ISSN=1664-462X

ABSTRACT=<p>The genus <italic>Panax</italic> is a valuable natural medicinal source used worldwide that contains high levels of triterpenoid saponins with extensive pharmacological activities. In past decades, molecular biotechnology and breeding techniques have been respectively used to generate omics data and information on cultivars primarily from <italic>Panax ginseng</italic> (ginseng), <italic>Panax quinquefolium</italic> (American ginseng), and <italic>Panax notoginseng</italic> (Sanqi) to biosynthesize valuable saponins, improve product quality, and conduct cost-controlled cultivation. Although much data have been produced, there are concerns that redundant data might be generated and that relatively scattered data might be overlooked. Therefore, many scientists desire a reliable, comprehensive omics database of the <italic>Panax</italic> genus that could save time and promote integrated analysis. Therefore, to provide all-inclusive, reliable, and valuable information on the <italic>Panax</italic> genus, PanaxGDB, an open comprehensive database that integrates data on omics and information on varieties, was established. The database contains information on nearly 600 compounds from 12 <italic>Panax</italic> species, draft genomic sequences with annotations and gene expression levels, single nucleotide polymorphisms, genome-wide association analysis based on agronomic traits, globally collected germplasm information, summaries, omics data of the <italic>Panax</italic> genus, and online versatile analytic tools. The <italic>Panax</italic> genus database will be updated when new data are released to continue serving as a central portal to boost research on the biology and functions of <italic>Panax</italic>. PanaxGDB is available at: <ext-link ext-link-type="uri" xlink:href="http://panaxGDB.ynau.edu.cn" xmlns:xlink="http://www.w3.org/1999/xlink">http://panaxGDB.ynau.edu.cn</ext-link>.</p>