AUTHOR=Flavell Richard B. 

TITLE=Wheat Breeding, Transcription Factories, and Genetic Interactions: New Perspectives

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.807884

DOI=10.3389/fpls.2022.807884

ISSN=1664-462X

ABSTRACT=<p>Epistatic interactions and negative heterosis have been shown to be associated with interchromosomal interactions in wheat. Physical gene-gene interactions between co-regulated genes clustered in “transcription factories” have been documented, and a genome-wide atlas of functionally paired, interacting regulatory elements and genes of wheat recently produced. Integration of these new studies on gene and regulatory element interactions, co-regulation of gene expression in “transcription factories,” and epigenetics generates new perspectives for wheat breeding and trait enhancement.</p>