AUTHOR=Huang Li-Jun , Wang Yukun , Lin Zeng , Jiang Dong , Luo Yong , Li Ning 

TITLE=The role of corepressor HOS15-mediated epigenetic regulation of flowering

JOURNAL=Frontiers in Plant Science

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.1101912

DOI=10.3389/fpls.2022.1101912

ISSN=1664-462X

ABSTRACT=<p>Regulation of gene expression underpins gene function and is essential for regulation of physiological roles. Epigenetic modifications regulate gene transcription by physically facilitating relaxation or condensation of target loci in chromatin. Transcriptional corepressors are involved in chromatin remodeling and regulate gene expression by establishing repressive complexes. Genetic and biochemical studies reveal that a member of the Groucho/Thymidine uptake 1 (Gro/Tup1) corepressor family, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 15 (HOS15), is recruited <italic>via</italic> the evening complex (EC) to the <italic>GIGANTEA</italic> (<italic>GI</italic>) promoter to repress gene expression, and modulating flowering time. Therefore, HOS15 connects photoperiodic pathway and epigenetic mechanism to control flowering time in plants. In addition, growing body of evidence support a diverse roles of the epigenetic regulator HOS15 in fine-tuning plant development and growth by integrating intrinsic genetic components and various environmental signals.</p>