AUTHOR=Maheshwari Chirag , Garg Nitin Kumar , Hasan Muzaffar , V Prathap , Meena Nand Lal , Singh Archana , Tyagi Aruna TITLE=Insight of PBZ mediated drought amelioration in crop plants JOURNAL=Frontiers in Plant Science VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.1008993 DOI=10.3389/fpls.2022.1008993 ISSN=1664-462X ABSTRACT=Water scarcity is a significant environmental limitation to plant productivity as drought-induced crop output losses are likely to outnumber losses from all other factors. In this context, triazole compounds have recently been discovered to act as plant growth regulators and multi-stress protectants such as heat, chilling, drought, waterlogging, heavy metals, etc. Paclobutrazol (PBZ) [(2RS, 3RS)-1-(4-chlorophenyl)-4, 4-dimethyl-2-(1H-1, 2, 4-trizol-1-yl)-pentan-3-ol] disrupts the isoprenoid pathway by blocking ent-kaurene synthesis, affecting gibberellic acid (GA) and abscisic acid (ABA) hormone homeostasis. PBZ also interferes with the concentrations of ethylene and cytokinin. Through a variety of physiological responses, PBZ improves plant survival under drought stress. Some of the documented responses include a decrease in transpiration rate (due to reduced leaf area), higher diffusive resistance, relieving reduction in water potential, greater relative water content, less water use, and increased antioxidant activity. In this review, we examined and discussed current findings as well as the prospective application of PBZ in regulating crop growth and ameliorating abiotic stresses. Furthermore, the influence of PBZ on numerous biochemical, physiological, and molecular processes has been thoroughly investigated, resulting in increased crop yield.