AUTHOR=Pan Lixia , Fonseca De Lima Cassio Flavio , Vu Lam Dai , De Smet Ive 

TITLE=A Comprehensive Phylogenetic Analysis of the MAP4K Family in the Green Lineage

JOURNAL=Frontiers in Plant Science

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2021.650171

DOI=10.3389/fpls.2021.650171

ISSN=1664-462X

ABSTRACT=Kinase-mediated phosphorylation impacts every basic cellular process. While MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASEs (MAP4Ks) are evolutionarily conserved, there is no comprehensive overview of the MAP4K family in the green lineage (Viridiplantae). Here, we identify putative MAP4K members from representative species of the two core groups in the green lineage, Chlorophyta –a diverse group of green algae – and Streptophyta – mostly freshwater green algae and land plants. From that, we infer the evolutionary relationships of MAP4K proteins through a phylogenetic reconstruction. We furthermore provide a classification in three distinct subclades for the MAP4Ks in the green lineage.