AUTHOR=Slavokhotova Anna A. , Rogozhin Eugene A. TITLE=Defense Peptides From the α-Hairpinin Family Are Components of Plant Innate Immunity JOURNAL=Frontiers in Plant Science VOLUME=11 YEAR=2020 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2020.00465 DOI=10.3389/fpls.2020.00465 ISSN=1664-462X ABSTRACT=

Plant immunity represents a sophisticated system, including both basal and inducible mechanisms, to prevent pathogen infection. Antimicrobial peptides (AMPs) are among the innate immunity components playing a key role in effective and rapid response against various pathogens. This review is devoted to a small family of defense peptides called α-hairpinins. The general characters of the family, as well as the individual features of each member, including biological activities, structures of precursor proteins, and spatial structures, are described. Possible applications of α-hairpinin peptides in drug design are discussed.