AUTHOR=Huang Qianfei , Zhang Jun , Wei Leyi , Guo Fei , Zou Quan 

TITLE=6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion

JOURNAL=Frontiers in Plant Science

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2020.00004

DOI=10.3389/fpls.2020.00004

ISSN=1664-462X

ABSTRACT=<sec><title>Motivation</title><p>The biological function of <italic>N</italic><sup>6</sup>-methyladenine DNA (6mA) in plants is largely unknown. Rice is one of the most important crops worldwide and is a model species for molecular and genetic studies. There are few methods for 6mA site recognition in the rice genome, and an effective computational method is needed.</p></sec><sec><title>Results</title><p>In this paper, we propose a new computational method called 6mA-Pred to identify 6mA sites in the rice genome. 6mA-Pred employs a feature fusion method to combine advantageous features from other methods and thus obtain a new feature to identify 6mA sites. This method achieved an accuracy of 87.27% in the identification of 6mA sites with 10-fold cross-validation and achieved an accuracy of 85.6% in independent test sets.</p></sec>