AUTHOR=Hahn-Löbmann Simone , Stephan Anett , Schulz Steve , Schneider Tobias , Shaverskyi Anton , Tusé Daniel , Giritch Anatoli , Gleba Yuri TITLE=Colicins and Salmocins – New Classes of Plant-Made Non-antibiotic Food Antibacterials JOURNAL=Frontiers in Plant Science VOLUME=10 YEAR=2019 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2019.00437 DOI=10.3389/fpls.2019.00437 ISSN=1664-462X ABSTRACT=

Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These food antimicrobials, along with approved biopharmaceuticals and vaccines, represent new classes of products manufactured in green plants as production hosts. We present results of new research and development and summarize regulatory, economic and business aspects of the antibacterial proteins colicins and salmocins as new food processing aids.