AUTHOR=Ye Fei , Ma Peng , Zhang Yuan-Yuan , Li Ping , Yang Fei , Fu Ying TITLE=Herbicidal Activity and Molecular Docking Study of Novel ACCase Inhibitors JOURNAL=Frontiers in Plant Science VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2018.01850 DOI=10.3389/fpls.2018.01850 ISSN=1664-462X ABSTRACT=
Acetyl-CoA carboxylase (ACCase) is an important target enzyme for the development of new bleaching herbicides. On the basis of structure-activity relationships and active subunit combinations, a series of novel 2-phenyl-3-cyclohexanedione enol ester derivatives was designed and synthesized by coupling and acylation reactions. The preliminary biological tests indicated good post-emergent herbicidal activity at a dosage of 150–300 g ai/ha, superior to that of clethodim against barnyard grass. Compound