AUTHOR=Zhou Gaofeng , Broughton Sue , Zhang Xiao-Qi , Ma Yanling , Zhou Meixue , Li Chengdao 

TITLE=Genome-Wide Association Mapping of Acid Soil Resistance in Barley (Hordeum vulgare L.)

JOURNAL=Frontiers in Plant Science

VOLUME=7

YEAR=2016

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2016.00406

DOI=10.3389/fpls.2016.00406

ISSN=1664-462X

ABSTRACT=<p>Genome-wide association studies (GWAS) based on linkage disequilibrium (LD) have been used to detect QTLs underlying complex traits in major crops. In this study, we collected 218 barley (<italic>Hordeum vulgare</italic> L.) lines including wild barley and cultivated barley from China, Canada, Australia, and Europe. A total of 408 polymorphic markers were used for population structure and LD analysis. GWAS for acid soil resistance were performed on the population using a general linkage model (GLM) and a mixed linkage model (MLM), respectively. A total of 22 QTLs (quantitative trait loci) were detected with the GLM and MLM analyses. Two QTLs, close to markers bPb-1959 (133.1 cM) and bPb-8013 (86.7 cM), localized on chromosome 1H and 4H respectively, were consistently detected in two different trials with both the GLM and MLM analyses. Furthermore, bPb-8013, the closest marker to the major Al<sup>3+</sup> resistance gene <italic>HvAACT1</italic> in barley, was identified to be QTL5. The QTLs could be used in marker-assisted selection to identify and pyramid different loci for improved acid soil resistance in barley.</p>