AUTHOR=de Ronde Dryas , Butterbach Patrick , Kormelink Richard 

TITLE=Dominant resistance against plant viruses

JOURNAL=Frontiers in Plant Science

VOLUME=5

YEAR=2014

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2014.00307

DOI=10.3389/fpls.2014.00307

ISSN=1664-462X

ABSTRACT=<p>To establish a successful infection plant viruses have to overcome a defense system composed of several layers. This review will overview the various strategies plants employ to combat viral infections with main emphasis on the current status of single dominant resistance (<italic>R</italic>) genes identified against plant viruses and the corresponding avirulence (<italic>Avr</italic>) genes identified so far. The most common models to explain the mode of action of dominant <italic>R</italic> genes will be presented. Finally, in brief the hypersensitive response (HR) and extreme resistance (ER), and the functional and structural similarity of <italic>R</italic> genes to sensors of innate immunity in mammalian cell systems will be described.</p>