AUTHOR=Yang Fen , Jacobsen Susanne , Jørgensen Hans J., Collinge David B., Svensson Birte , Finnie Christine 

TITLE=Fusarium graminearum and Its Interactions with Cereal Heads: Studies in the Proteomics Era

JOURNAL=Frontiers in Plant Science

VOLUME=4

YEAR=2013

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2013.00037

DOI=10.3389/fpls.2013.00037

ISSN=1664-462X

ABSTRACT=<p>The ascomycete fungal pathogen <italic>Fusarium graminearum</italic> (teleomorph stage: <italic>Gibberella zeae</italic>) is the causal agent of <italic>Fusarium</italic> head blight in wheat and barley. This disease leads to significant losses of crop yield, and especially quality through the contamination by diverse fungal mycotoxins, which constitute a significant threat to the health of humans and animals. In recent years, high-throughput proteomics, aiming at identifying a broad spectrum of proteins with a potential role in the pathogenicity and host resistance, has become a very useful tool in plant-fungus interaction research. In this review, we describe the progress in proteomics applications toward a better understanding of <italic>F. graminearum</italic> pathogenesis, virulence, and host defense mechanisms. The contribution of proteomics to the development of crop protection strategies against this pathogen is also discussed briefly.</p>