ORIGINAL RESEARCH article

Front. Physiol.

Sec. Computational Physiology and Medicine

Volume 16 - 2025 | doi: 10.3389/fphys.2025.1581699

Multimodal Deep Learning for Freezing of GaitDetection in Parkinson’s Disease UsingWearable Sensors

Provisionally accepted
  • 1King Faisal University, Al-Ahsa, Saudi Arabia
  • 2Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan

The final, formatted version of the article will be published soon.

Freezing of Gait (FoG) is a disabling symptom in Parkinson’s Disease (PD) that substantially4 affects patient ability to movement and hence quality of life. The current research aims to introduce5 a framework that is based on advanced AI techniques such as deep learning techniques that6 utilizes a more special type of deep learning models known as Convolutional Neural Networks7 (CNNs) for spatial characteristics discover and a sequence based model known as Bidirectional8 Long Short-Term Memory (BiLSTM) networks for temporal modeling, complemented by an9 attention mechanism to pinpoint essential gait features. The approach is trained with multimodal10 sensor data across sources like tDCS FoG, DeFOG, Daily Living, and Hantao’s Multimodal11 datasets in order to establish robustness and generalizability over populations of varied natures.12 Preeminent issues of sensor noise, inter-subject variation, and class imbalance are countered13 with deep preprocessing operations, i.e., sensor fusion, normalization, and data augmentation.14 The model exhibits high performance with accuracy (98%), F1-score (94%), and AUC (96%) over15 existing methods for detecting FoG episodes. The present research shows the ability of AI-aided16 analysis of wearable sensor data in enhancing diagnostic accuracy, therapy personalization, and17 monitoring of unfortunate people having neurological disability and advances the wider context of18 AI application in medicine.

Keywords: Wearable sensor, freezing of gait, deep learning, attention mechanism, Artifcial intelligence

Received: 28 Feb 2025; Accepted: 14 Apr 2025.

Copyright: © 2025 Al-Adhaileh, Wadood, Aldhyani, Khan, Uddin and Al-Nefaie. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Theyazn H.H Aldhyani, King Faisal University, Al-Ahsa, Saudi Arabia

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