SYSTEMATIC REVIEW article
Front. Physiol.
Sec. Gastrointestinal Sciences
Volume 16 - 2025 | doi: 10.3389/fphys.2025.1511391
The Effects of Heart Rate Variability Biofeedback on Functional Gastrointestinal Disorders: A Scoping Review
Provisionally accepted
- 1Department of Surgery, School of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, Auckland, New Zealand
- 2Auckland Bioengineering Institute, Faculty of Engineering, University of Auckland, Auckland, Auckland, New Zealand
- 3Alimetry Ltd., Auckland, Auckland, New Zealand
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Functional Gastrointestinal Disorders (FGID) are a group of symptom-based disorders that occur across the alimentary tract and have a high prevalence globally in both adults and children. These symptoms are chronic and/or recurrent and often have substantial effects on quality of life. Their incidence is tied to multiple factors, including gut-brain axis imbalance, which includes autonomic dysregulation related to a relative withdrawal of vagal activity. Heart rate variability biofeedback (HRVB) is a non-invasive intervention that can influence autonomic activity and has shown benefit for diverse conditions including depression and anxiety, however the evidence of its effect has not yet been systematically assessed in FGIDs. This scoping review aimed to collate and evaluate the available literature regarding HRVB and FGIDs.We systematically searched four medical databases. Four interventional studies using HRVB in FGIDs met inclusion criteria.Results: Studies were heterogeneous, including both paediatric and adult patients, as well different subtypes of FGID. Two of the four studies demonstrated significant symptom improvements from HRVB while the other two found no significant difference. Discussion: Our findings suggested that at least six weeks of HRVB is required to observe an impact on FGID symptoms. We provide recommendations for future studies of HRVB in FGIDs, which are needed. Evidence on HRVB for FGID is still emerging , but appears promising when administered optimally.
Keywords: heart rate variability 1, Functional Gastrointestinal Disorder 2, Biofeedback 3, Disorder of Gut Brain Interaction 4, resonance breathing
Received: 14 Oct 2024; Accepted: 24 Apr 2025.
Copyright: © 2025 Pereira, Fu, Xu, Gharibans and O'Grady. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Greg O'Grady, Department of Surgery, School of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, 1142, Auckland, New Zealand
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