Panqi He Limin Liao ^*

• Capital Medical University, Beijing, China

Purpose: This study aims to use the Glomerular Filtration Rate (GFR) measured by dynamic renal scintigraphy (Gates method) as a standard to investigate the applicability of two creatinine (Cr)-based GFR estimation equations in Chinese neurogenic bladder (NB) patients of different genders, age groups, and GFR stages.Methods: GFR measured by 99mTc-DTPA renal dynamic imaging was sGFR, GFR measured by the new serum creatinine (Cr)-based Chronic Kidney Disease Epidemiology Collaborative Group (CKD-EPl) equation was EPI-GFR, and GFR measured by the equation for the Estimated Glomerular Filtration Rate of Chronic Kidney Disease Patients in China was cGFR. Statistical Analysis: Pearson's correlation and linear regression were used to compare the differences, absolute differences, precision, and accuracy of the 2 equations for GFR and sGFR to determine which formula performs better in the assessment of patients with NB.Results: A total of 99 NB patients participated in the final analysis, Both cGFR and EPI-GFR were moderately correlated with sGFF in both males and females.The overall staging accuracy of EPI-GFR and sGFR was also significantly higher than the accuracy of cGFR and sGFR. Among patients staged by GFR, only patients with GFR in the range of 60-89 mL/min/1.73 m 2 had moderate correlation between cGFR and EPI-GFR and sGFR, and the rest of the staged patients had low correlation between cGFR and EPI-GFR and sGFR. Conclusion: Researchers found that the Chinese CKD patient equation performed well in NB patients aged 20-25, while the race-neutral CKD-EPI equation performed better in NB patients aged 26-35..