Skip to main content

BRIEF RESEARCH REPORT article

Front. Physiol.
Sec. Reproductive and Mating Physiology
Volume 15 - 2024 | doi: 10.3389/fphys.2024.1489780

Optimal Management Strategies for Promoting Gestational Extension in Dichorionic Diamniotic Twin Pregnancies

Provisionally accepted
Caixia Chen Caixia Chen 1Changyou Fan Changyou Fan 2Bufei Wang Bufei Wang 1Ping Zhu Ping Zhu 1*
  • 1 Department of Obstetrics, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, China
  • 2 The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong Province, China

The final, formatted version of the article will be published soon.

    Background: Preterm birth is a significant concern in multiple pregnancies, warranting effective strategies to improve outcomes. Delaying delivery of the second fetus is crucial for reducing perinatal mortality rates. Case Presentation: In a dichorionic diamniotic twin pregnancy, one fetus experienced premature rupture of membranes (PROM) at 16+6 weeks gestation. Proactive fetal reduction through potassium chloride injection and emergency cervical cerclage at 19+1 weeks successfully extended the pregnancy to 39+5 weeks, resulting in a notable 160-day prolongation. Postoperative management encompassed comprehensive tocolytic therapy. Conclusions: The combined approach of proactive fetal reduction and emergency cervical cerclage proved successful in managing PROM in dichorionic diamniotic twin pregnancies. This innovative strategy offers a promising clinical solution for optimizing outcomes and prolonging gestation in high-risk multiple pregnancies, underscoring the importance of tailored interventions in complex obstetric scenarios.

    Keywords: Twin pregnancy, Premature rupture of membranes, Delayed interval delivery, Fetal reduction, Cervical cerclage

    Received: 01 Sep 2024; Accepted: 24 Oct 2024.

    Copyright: © 2024 Chen, Fan, Wang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ping Zhu, Department of Obstetrics, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.