AUTHOR=Chen Xin , Zhang Jiexin , Lin Yuan , Li Yan , Wang Han , Wang Zhanhao , Liu Huawei , Hu Yonghe , Liu Lei TITLE=Mechanism, prevention and treatment of cognitive impairment caused by high altitude exposure JOURNAL=Frontiers in Physiology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1191058 DOI=10.3389/fphys.2023.1191058 ISSN=1664-042X ABSTRACT=

Hypobaric hypoxia (HH) characteristics induce impaired cognitive function, reduced concentration, and memory. In recent years, an increasing number of people have migrated to high-altitude areas for work and study. Headache, sleep disturbance, and cognitive impairment from HH, severely challenges the physical and mental health and affects their quality of life and work efficiency. This review summarizes the manifestations, mechanisms, and preventive and therapeutic methods of HH environment affecting cognitive function and provides theoretical references for exploring and treating high altitude-induced cognitive impairment.