AUTHOR=Sato Shuji , Shimizu Kazuhiro , Takahashi Mao , Masai Motoyuki , Nagakawa Osamu , Uchino Junji , Suzuki Toshihiro , Sato Yuka , Iwai Noriko , Shirai Kohji TITLE=Changes in blood pressure and arterial stiffness monitored using the cardio–ankle vascular index during hemodialysis JOURNAL=Frontiers in Physiology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1133037 DOI=10.3389/fphys.2023.1133037 ISSN=1664-042X ABSTRACT=
During hemodialysis (HD), blood pressure (BP) changes are frequently observed. However, the mechanism of BP changes during HD has not been fully clarified. The cardio–ankle vascular index (CAVI) reflects the arterial stiffness of the arterial tree from the origin of the aorta to the ankle independent from BP during measurement. Additionally, CAVI reflects functional stiffness in addition to structural stiffness. We aimed to clarify the role of CAVI in regulating the BP system during HD. We included 10 patients undergoing 4-hour HD (total 57 HD sessions). Changes in the CAVI and various hemodynamic parameters were evaluated during each session. During HD, BP decreased and CAVI significantly increased (CAVI, median [interquartile range]; 9.1 [8.4–9.8] [0 min] to 9.6 [9.2–10.2] [240 min],