AUTHOR=Monod Cécile , Kotzaeridi Grammata , Eppel Daniel , Linder Tina , Bozkurt Latife , Hösli Irene , Göbl Christian S. , Tura Andrea 

TITLE=Assessment of glucose levels in pregnant women with history of COVID-19 in a case-control study

JOURNAL=Frontiers in Physiology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.988361

DOI=10.3389/fphys.2022.988361

ISSN=1664-042X

ABSTRACT=<p>Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection may negatively affect glucose metabolism. This study aims to assess glucose levels, prevalence of gestational diabetes mellitus (GDM) and perinatal outcome in women with history of COVID-19. To this purpose, a group of 65 patients with history of COVID-19 and 94 control patients were retrospectively recruited among pregnant women who attended the pregnancy outpatient department between 01/2020 and 02/2022. Glucose data from an oral glucose tolerance test (OGTT), GDM status and obstetric complications were assessed. We observed no differences in average (<italic>p</italic> = 0.37), fasting (<italic>p</italic> = 0.62) or post-load glucose concentrations (60 min: <italic>p</italic> = 0.19; 120 min: <italic>p</italic> = 0.95) during OGTT. A total of 15 (23.1%) women in the COVID-19 group and 18 (19.1%) women in the control group developed GDM (<italic>p</italic> = 0.55). Moreover, caesarean section rate, weight percentiles and pregnancy outcomes were comparable between the groups (<italic>p</italic> = 0.49). In conclusion, in this study we did not identify a possible impact of COVID-19 on glucose metabolism in pregnancy, especially with regard to glucose concentrations during the OGTT and prevalence of GDM.</p>