AUTHOR=Louro Ana F. , Virgolini Nikolaus , Paiva Marta A. , Isidro Inês A. , Alves Paula M. , Gomes-Alves Patrícia , Serra Margarida TITLE=Expression of Extracellular Vesicle PIWI-Interacting RNAs Throughout hiPSC-Cardiomyocyte Differentiation JOURNAL=Frontiers in Physiology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.926528 DOI=10.3389/fphys.2022.926528 ISSN=1664-042X ABSTRACT=
Extracellular Vesicles (EV) play a critical role in the regulation of regenerative processes in wounded tissues by mediating cell-to-cell communication. Multiple RNA species have been identified in EV, although their function still lacks understanding. We previously characterized the miRNA content of EV secreted over hiPSC-cardiomyocyte differentiation and found a distinct miRNA expression in hiPSC-EV driving its