AUTHOR=Fang HaoHang , Zhuang ZhenXiao , Huang LuoDong , Niu Jin , Zhao Wei 

TITLE=A Newly Isolated Strain of Haematococcus pluvialis GXU-A23 Improves the Growth Performance, Antioxidant and Anti-Inflammatory Status, Metabolic Capacity and Mid-intestine Morphology of Juvenile Litopenaeus vannamei

JOURNAL=Frontiers in Physiology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.882091

DOI=10.3389/fphys.2022.882091

ISSN=1664-042X

ABSTRACT=<p><italic>Haematococcus pluvialis</italic> can be used as a green additive in aquafeeds due to it contains rich astaxanthin and polyunsaturated fatty acid. In the present study, a newly strain of <italic>H. pluvialis</italic> GXU-A23 with high concentration of astaxanthin was firstly isolated by a newly culture strategy in our laboratory. In addition, <italic>H. pluvialis</italic> GXU-A23 was applied in the <italic>Litopenaeus vannamei</italic> feed for determining whether it has positive effects on the growth performance, antioxidant and anti-inflammatory status, metabolic capacity and mid-intestine morphology of juvenile <italic>L. vannamei</italic>. Shrimp with 0.63 g approximately initial body weight were fed diets supplemented with/without 50 g/kg <italic>H. pluvialis</italic> GXU-A23. After 8 weeks feeding intervention, significantly higher growth performance of <italic>L. vannamei</italic> was obtained in the <italic>H. pluvialis</italic> GXU-A23 treatment group compared to the control group (<italic>p</italic> &lt; 0.05). At the same time, <italic>L. vannamei</italic> fed with <italic>H. pluvialis</italic> GXU-A23 acquired significantly better antioxidant and anti-inflammatory status than the control group (<italic>p</italic> &lt; 0.05). In addition, higher RNA expression level of hepatopancreas digestive enzyme, hepatopancreas lipid and glucose metabolic enzymes as well as better mid-intestine morphology were found in the <italic>H. pluvialis</italic> GXU-A23 treatment group than the control group (<italic>p</italic> &lt; 0.05). These results indicated that 50 g/kg <italic>H. pluvialis</italic> GXU-A23 was suitable for the <italic>L. vannamei</italic> feed, which could improve the growth performance, antioxidant and anti-inflammatory status, metabolic capacity and mid-intestine morphology of juvenile <italic>L. vannamei.</italic></p>