AUTHOR=Juttukonda Meher R. , Vaclavu Lena , Kirkham Fenella J. , Fields Melanie E. , Bush Adam M. TITLE=Editorial: Cerebral oxygen supply and demand in sickle cell disease: Evidence of local ischemia despite global hyperemia JOURNAL=Frontiers in Physiology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.1079889 DOI=10.3389/fphys.2022.1079889 ISSN=1664-042X