AUTHOR=Zhang Xiaoshuai , Li Sheng , Liu Suning 

TITLE=Juvenile Hormone Studies in Drosophila melanogaster

JOURNAL=Frontiers in Physiology

VOLUME=12

YEAR=2022

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.785320

DOI=10.3389/fphys.2021.785320

ISSN=1664-042X

ABSTRACT=<p>In the field of insect endocrinology, juvenile hormone (JH) is one of the most wondrous entomological terms. As a unique sesquiterpenoid hormone produced and released by the endocrine gland, corpus allatum (CA), JH is a critical regulator in multiple developmental and physiological processes, such as metamorphosis, reproduction, and behavior. Benefited from the precise genetic interventions and simplicity, the fruit fly, <italic>Drosophila melanogaster</italic>, is an indispensable model in JH studies. This review is aimed to present the regulatory factors on JH biosynthesis and an overview of the regulatory roles of JH in <italic>Drosophila.</italic> The future directions of JH studies are also discussed, and a few hot spots are highlighted.</p>