AUTHOR=Tan Albert Yi-Wey , Hamzah Sareena-Hanim , Huang Chih-Yang , Kuo Chia-Hua 

TITLE=Pre-exercise Carbohydrate Drink Adding Protein Improves Post-exercise Fatigue Recovery

JOURNAL=Frontiers in Physiology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.765473

DOI=10.3389/fphys.2021.765473

ISSN=1664-042X

ABSTRACT=<p><bold>Purpose:</bold> This study aimed to assess the requirement of protein in pre-exercise carbohydrate drinks for optimal endurance performance at high intensity and post-exercise fatigue recovery.</p><p><bold>Methods:</bold> Endurance performance at 85% <inline-formula><mml:math id="INEQ1" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mover accent="true"><mml:mtext>V</mml:mtext><mml:mo>.</mml:mo></mml:mover><mml:mo>⁢</mml:mo><mml:msub><mml:mtext>O</mml:mtext><mml:mn>2</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula><sub>peak</sub> of young men (age 20 ± 0.9 years, <inline-formula><mml:math id="INEQ2" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mover accent="true"><mml:mtext>V</mml:mtext><mml:mo>.</mml:mo></mml:mover><mml:mo>⁢</mml:mo></mml:mrow></mml:math></inline-formula><sub>2peak</sub> 49.3 ± 0.3 L/min) was measured for two consecutive days using cycling time to exhaustion and total work exerted 2 h after three isocaloric supplementations: RICE (50 g, protein: 1.8 g), <italic>n</italic> = 7; SOY + RICE (50 g, protein: 4.8 g), <italic>n</italic> = 7; and WHEY + RICE (50 g, protein: 9.2 g), <italic>n</italic> = 7.</p><p><bold>Results:</bold> Endurance performance was similar for the three supplemented conditions. Nevertheless, maximal cycling time and total exerted work from Day 1 to Day 2 were improved in the WHEY + RICE (+21%, <italic>p</italic> = 0.05) and SOY-RICE (+16%, <italic>p</italic> = 0.10) supplemented conditions, not the RICE supplemented condition. Increases in plasma interleukin-6 (IL-6) were observed 1 h after exercise regardless of supplemented conditions. Plasma creatine kinase remained unchanged after exercise for all three supplemented conditions. Increases in ferric reducing antioxidant power (FRAP) after exercise were small and similar for the three supplemented conditions.</p><p><bold>Conclusion:</bold> Adding protein into carbohydrate drinks provides no immediate benefit in endurance performance and antioxidant capacity yet enhances fatigue recovery for the next day. Soy-containing carbohydrate drink, despite 50% less protein content, shows similar fatigue recovery efficacy to the whey protein-containing carbohydrate drink. These results suggest the importance of dietary nitrogen sources in fatigue recovery after exercise.</p>