AUTHOR=Di Maro Martina , Cataldi Mauro , Santillo Mariarosaria , Chiurazzi Martina , Damiano Simona , De Conno Barbara , Colantuoni Antonio , Guida Bruna 

TITLE=The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19

JOURNAL=Frontiers in Physiology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.653985

DOI=10.3389/fphys.2021.653985

ISSN=1664-042X

ABSTRACT=<p>The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally interact with each other, a mechanism that could have a more general physiological relevance than only COVID-19 infection.</p>