AUTHOR=Cruz-Montecinos Carlos , Pérez-Alenda Sofía , Querol Felipe , Cerda Mauricio , Maas Huub TITLE=Changes in Muscle Activity Patterns and Joint Kinematics During Gait in Hemophilic Arthropathy JOURNAL=Frontiers in Physiology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2019.01575 DOI=10.3389/fphys.2019.01575 ISSN=1664-042X ABSTRACT=
Hemophilic arthropathy is the result of repetitive intra-articular bleeding and synovial inflammation. In people with hemophilic arthropathy (PWHA), very little is known about the neural control of individual muscles during movement. The aim of the present study was to assess if the neural control of individual muscles and coordination between antagonistic muscle pairs and joint kinematics during gait are affected in PWHA. Thirteen control subjects (CG) walked overground at their preferred and slow velocity (1 m/s), and 14 PWHA walked overground at the preferred velocity (1 m/s). Joint kinematics and temporal gait parameters were assessed using four inertial sensors. Surface electromyography (EMG) was collected from gluteus maximus (GMAX), gluteus medius (GMED), vastus medialis (VM), vastus lateralis (VL), rectus femoris (RF), medial gastrocnemius (MG), lateral gastrocnemius (LG), soleus (SOL), tibialis anterior (TA), semitendinosus (ST), and biceps femoris (BF). Waveforms were compared using the time-series analysis through statistical parametric mapping. In PWHA compared to CG, EMG amplitude during the stance phase was higher for LG (for both velocities of the CG), BF (slow velocity only), and ST (preferred velocity only) (